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Premature rupture of amniotic membranes and neonatal infection: Predictive value of bacteriologic cultures from different sites

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Abstract

Bacteriologic cultures were obtained from swabs of vagina and placental membranes, and pieces of placenta from 204 women with prolonged rupture of membranes. The frequency of positive isolation of bacteria increased with prolongation of the time between rupture of membranes and delivery. In 104 infants born to these mothers clinical studies and bacterial cultures of swabs from nose, umbilicus, gastric aspirate and blood were carried out, and correlated with cultures of swabs from vagina and placenta. In 80 per cent of cases identical organisms were isolated, from sites of neonatal infection, and vaginal swabs. Positive cultures from placental tissues showed the maximal correlation with mortality, while gastric aspirate proved to be a good predictor of severe infection in the newborn.

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Udani, R.H., Vaze, S., Reys, M. et al. Premature rupture of amniotic membranes and neonatal infection: Predictive value of bacteriologic cultures from different sites. Indian J Pediatr 47, 137–140 (1980). https://doi.org/10.1007/BF02822880

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