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Prognostic indicators in Indian childhood cirrhosis

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Abstract

Nineteen cases of Indian childhood cirrhosis (ICC) were studied for determining prognostic indicators. Lower serum bilirubin and high serum alkaline phosphatase were associated with good prognosis. Mere presence of hyaline did not influence the clinical and biochemical parameters, however excess hyaline formation was associated with rapidly deteriorating course. Extent of reticulin condensation had no specific significance, but extensive fibrosis was associated with low serum alkaline phosphatase level and shorter survival period. There were six survivors in the study with a follow up upto 26 months and repeat liver biopsies in most of them showed very little changes.

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Authors and Affiliations

  1. Department of Pediatrics, Jawaharlal Institute of Post-graduate Medical Education and Research, 605 006, Pondicherry

    R. Madhavan M.D., Ishwar C. Verma M.R.C.P., M.A.M.S. (Associate Professor in Pediatrics), Ramesh K. Puri M.D., D.C.H. & Panna Choudhury M.D., D.C.H.

Authors
  1. R. Madhavan M.D.
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  2. Ishwar C. Verma M.R.C.P., M.A.M.S.
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  3. Ramesh K. Puri M.D., D.C.H.
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  4. Panna Choudhury M.D., D.C.H.
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Madhavan, R., Verma, I.C., Puri, R.K. et al. Prognostic indicators in Indian childhood cirrhosis. Indian J Pediatr 48, 593–598 (1981). https://doi.org/10.1007/BF02821579

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