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Novel oxindole derivatives and their biological activity

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Abstract

The antifungal activity of fourteen novel derivatives of oxindole with side chain was studied using representatives of toxinogenic, phytopathogenic and dermatophytic filamentous fungi. Derivatives with exocyclic C=C bond in position C-3 exhibited a higher antifungal activity compared with derivatives with an exocyclic C−C bond in the same position. The strongest antifungal effects were shown by 3-(-2-thienoylmethylidene)-indol-2(3H)-ones.

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Correspondence to J. Strigácová.

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Strigácová, J., Hudecová, D., Mikulášová, M. et al. Novel oxindole derivatives and their biological activity. Folia Microbiol 46, 187–192 (2001). https://doi.org/10.1007/BF02818531

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  • DOI: https://doi.org/10.1007/BF02818531

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