Abstract
Rectal swabs from children, aged from 1 month to 5 yr with diarrhea brought to the outpatient clinic of the Children Hospital, Riyadh, Kingdom of Saudi Arabia were examined for the presence of common enteric pathogens both bacterial and viral. Important diarrheal pathogens were isolated from 30·6 per cent of the children. Rotavirus was detected from 16·7 per cent of the patients followed by EPEC 5·5 per cent, ETEC 4·6 per cent and Shigella sp. 3·7 per cent. No organism of Salmonella group was found in this group of children. Rotavirus was predominant in age groups between 1 month to 2 yr. Antibiotic resistance were less common in pathogenic bacteria but more prominent in the non pathogenic Esch. coli isolated from the stool. Fifty four of the Esch coli were resistant to 4–6 commonly used antibiotics such as tetracycline, ampicillin, chloramphenicol, kanamycin, streptomycin and cotrimoxazole. This high incidence of multiple resistance in the population may be attributed to indiscriminate use of antibiotics.
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Cruickshank R: Enteric infection: gastroenteritis, dysentery typhoid, cholera.Epidemiology and community health in warm climate countries. Cruickshank R. Standard KL, Russel HBL, (eds). Edinburgh: Churchill Livingston, 1976, 107
Soenarto Y, Sebodo T, Suryantoro P, Kirshnomurti, Haksohusodo S,et al.: Bacteria, parsitic agents and rotaviruses associated with acute diarrhoea in hospital inpatient Indonesian Children:Trans Roy Soc Trop Med Hyg 77: 724, 1983
Escheverria P, Blacklow NR, Vollet JL, Ulangco CV, Cukor G, Soriano VB, Dunpont HL, Cross JH, Orskov F, Orskov I: Reovirus like agent and EnterotoxigenicEscheriachia coli infection in pediatric diarrhoea in the Philippines.J Infect Dis 138: 362, 1978
Ryder RW, Sack DA, Kapikian AZ, Mac-Laughlin JC, Chakravarty J, Rahman ASMM, Merson MH, Wells JG:Enterotoxigenic coli. and reovirus like agent in rural Bangladesh.Lancet i 659, 1976
Evans DG, Evans DJ, Pierce NF: Difference in the response of rabbit small intestine to heat liable and heat stable enterotoxins ofEscherichia coli.Infect Immun 7: 873, 1973
Sack RB: Human diarrhoeal diseases caused by enterotoxigenicEscherichia coli.Ann Rev Microbiol 29: 333, 1975
Huq MI: A simple laboratory method for the diagnosis ofV. cholerae.Trans Roy Soc Trop Med Hyg 73: 553, 1979
Huq MI, Kibriya AKMG, Rahman MM: Bacteriological diagnosis of Shigella in laboratory and field conditions.Proceedings of the International Conference on Shigellosis: a continuing global problem. Cox’s Bazar. Bangladesh 15–20 June, 1981. Rahman MM, Greenough WB III, Novak NR, Rahman S (eds); ICDDR, B, Dhaka, 1983, p 107
Gurrant RL, Brunton LL, Schnaitman TC, Rebhum LI, Gilman AG: Cyclic adenosine monophophate and alteration of Chinese hamster ovary cell morphology: a rapid, sensitivein-vitro test for the enterotoxins ofV. cholerae andEscherichia coli.Infect Immun 10: 320, 1974
Dean AG, Ching YC, William RG, Harden LB: Test forEscherichia coli enterotoxin using infant mice: application in a study of diarrhoea in children in Honolulu.J Infect Dis 125: 407, 1972
Yoken RH, Kim HW, Clem T, Wyatt RG, Kalica AR, Chanock RM, Kapikian AZ: Enzyme linked immunosorbent assary (ELISA) for detection of human reovirus like agent of infantile gastroenteritis,Lancet ii: 263, 1977
Bauer AW, Kirby WMM, Sherris JC, Twick M: Antibiotic susceptibility testing by a standardised single disk method.Am J Clin Pathol 45: 493, 1966
Al-Sowaygh IA, Shibli AM: Incidence of antimicrobial resistance among enterobacteriacae isolated in Riyadh.Current Microbiol 5: 43, 1981
Rowland MGM, Davies H, Patterson S: Virus and diarrhoea in West African and London: a collaborative study.Trans Roy Soc Trop Med Hyg 72, 95, 1978
Black RE, Merson MH, Rahman ASMM, Yunus M, Alim ARMA, Huq MI, Yolken RH, Curlin GT: A two years study of bacterial, viral and parasitic agents associated with diarrhoea in rural Bangladesh.J Infect Dis 142 660, 1980
Gurwith MJ, Williams TW: Gastroenteritis in children: a two years review in Manitoba,I. Etiology J Infect Dis 136: 239, 1977
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Huq, M.I., Al Swailem, A.R., Fares, S. et al. Studies on the etiologic agents of infantile diarrhea in Riyadh. Indian J Pediatr 52, 293–298 (1985). https://doi.org/10.1007/BF02754862
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DOI: https://doi.org/10.1007/BF02754862