Abstract
Associations studies were attempted between the type of feeding, duration, and time of starting of solid foods in infancy and the incidence of insulin-dependent diabetes mellitus ( IDDM). The study subjects comprised 52 IDDM patients and 52 control subjects matched for sex, age, social status, country, geographical location and selected from pediatric departments of different hospitals in Tehran. Diabetic children (21 boys, 31 girls) were of the ages of 1.5 to 14 years. Information about the pattern of their feeding at the first two years of life were collected through questionnaires administered to the mothers. The questionnaire was designed to evaluate the duration of complete or partial breast-feeding and the age at which dietary products containing cow’s milk were introduced into the diet. A large proportion of the diabetic children rather than the control children had been breast-fed, and the risk of IDDM among children who had not been breast-fed was below unity. No significant difference in the duration of breast-feeding was observed between diabetic and control group. Our data do not support the existence of a protective effect of breast-feeding on the risk of IDDM, nor do the data indicate that early exposure to cow’s milk and dairy products has any influence on the development of IDDM.
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References
Meloni T, Marinaro AMet al. IDDM and early infant feeding.Diabetic-Care 1997; 20(3): 340–342.
Mijac V, Arrieta Jet al. Role of environmental factors in the development of insulin-dependent diabetes mellitus (IDDM) in Venezuelan children.Invest Clin 1995; 36(2): 73–82.
Verge Cf. Howard NJet al. Environment factors in childhood IDDM.Diabetes Care 1994; 17(12): 1381–1389.
Soltesz G. Jeges Set al. Non-genetic risk determinats for type 1 diabetes mellitus in childhood.Acta Pediatr. 1994; 83(7): 730–735.
Karjalaineny, Martinjm, Knip Met al. A bovine albumin peptide as a possible trigger of insulindependent diabetes mellitus.Nengly Med 1992; 327: 302–307.
Nerup, Platz P, Ortved Andersonet al. HL-Antigens and diabetes mellitus.Lancet 1974; 11: 846–866.
Borch-Johnsen K, Joner Get al. Relation between breastfeeding and incidence of insulin-dependent diabetes mellitus.Lancet 1989; 2:1083–1086.
Norris JM, Scott FW. A meta-analysis of infant diet and insulin-dependent diabetes mellitus: do biasea play a role?Epidemiology 1996; 7: 87–92.
Vitanen SM, Rasanen L, Aro A,et al. Infant feeding in finnish children < 7 year of age with newly diagnosed IDDM.Diabetes Care 1991; 14: 415–417.
Gerstein HC. Cow’s milk exposure and type 1 diabetes mellitus: a critical overview of the clinical literature.Diabetes Care 1994; 17 :13–19.
Work Group on Cow’s Milk Protein and Diabetes Mellitus. AAP infant feeding practices and their possible relationship to the etiology of diabetes mellitus.Pediatrics 1994; 94: 752–754.
Schatz DA, Mac Laren NK. Cow’s milk and insulin dependent diabetes mellitus: innocent until proven guilty.JAMA 1996; 276 : 647–648.
Norris JM, Beaty B, Klingen Smith Get al. Lack of association between early exposure to cow’s milk protein and B-cell autoimmunity: Diabetes autoimmunity study in the young (DAISY).JAMA 1996; 276 :609–614.
Scott FW. AAP recommendations on cow milk, soy and early infant feeding.Pediatrics 1995; 96: 515–516.
Scott FW, Norris JM, Kolb M? Milk and type I diabetes examining the evidence and broadening the focus.Diabetes Care 1996; 19: 379–383.
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Esfarjani, F., Azar, M.R. & Gafarpour, M. IDDM and early exposure of infant to cow’s milk and solid food. Indian J Pediatr 68, 107–110 (2001). https://doi.org/10.1007/BF02722023
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DOI: https://doi.org/10.1007/BF02722023