Abstract
This study examined the possibility of using biological monitoring to assess deltamethrin exposure among greenhouse workers. The synthetic pyrethroid deltamethrin was sprayed in five greenhouses by cold fog generators, and the exposure was biologically monitored by analysing the concentration of its metabolite, 3-phenoxybenzoic acid, by a gas chromatographic method after derivatization with pentafluorobenzyl bromide. 3-Phenoxybenzoic acid was found in the urine of two of the ten workers studied. The urine concentration of the metabolite varied from 2.4 to 51.7 μg/l. These results show that 3-phenoxybenzoic acid is suitable for biological monitoring for the assessment of exposure to deltamethrin.
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References
He F, Wang S, Liu L, Chen S, Zhang Z, Sun J (1989) Clinical manifestations and diagnosis of acute pyrethroid poisoning. Arch Toxicol 63:54–58
Manninen A, Kangas J, Klen T, Savolainen H (1986) Exposure of Finnish farm workers to phenoxy acid herbicides. Arch Environ Contam Toxicol 15:107–111
Manninen A, Kangas J, Tuomainen A, Tahvonen R (1996) Exposure to insecticides in the use of cold fog generator in greenhouses. Toxicol Environm Chem (in press)
Miyamoto J, Beynon K, Roberts T, Hemingway R, Swaine H (1981) The chemistry, metabolism and residue analysis of synthetic pyrethroids. Pure Appl Chem 53:1967–2022
Ruzo L, Engel J, Casida J (1978) Decamethrin metabolites from oxidative, hydrolytic and conjugative reactions in mice. J Agric Food Chem 27:725–731
Ruzo L, Unai T, Casida J (1979) Decamethrin metabolism in rats. J Agric Food Chem 26:918–925
Vaysse M, Giudicelli J, Devarex P, L'Hotellier M (1984) Decis: analytical methods for pesticides and plant growth regulators, vol XIII. Academic Press, New York, pp 53–68
Vijverberg H, Van den Bercken J (1982) Action of pyrethroid insecticides on the vertebrate nervous system. Neuropathol Appl Neurobiol 8:421–440
Worthing CR, Hance RJ (eds) (1991) The Pesticide Manual: a world compendium, 9th Ed. British Crop Protection Council. Surrey, UK
Wu Y, Xiao-Yen G, Chun-Ling L (1994) Determination of pyrethroids in human urine by gas chromatography. Biomed Environm Sci 7:216–221
Yao P, Li Y, Zhang X, He F (1989) Biological monitoring of deltamethrin metabolites in spraymen and one suicide patient by HPLC. In: Sakurai H (ed.) VII Int Conf Epidemiology in Occupational Health. Tokyo October, Elsevier Science Publishers, Amsterdam, pp 219–222
Yao P, Li Y, Ding Y, He F (1992) Biological monitoring of deltamethrin in sprayers by HPLC method. J Hyg Epidemiol Microbiol Immunol 1:31–36
Zhang Z, Sun J, Chen S, Wu Y, He F (1991) Levels of exposure and biological monitoring of pyrethroids in spraymen. Br J Ind Med 48:82–86
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Tuomainen, A., Kangas, J., Liesivuori, J. et al. Biological monitoring of deltamethrin exposure in greenhouses. Int. Arch Occup Environ Heath 69, 62–64 (1996). https://doi.org/10.1007/BF02630740
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DOI: https://doi.org/10.1007/BF02630740