Summary
We investigated the zinc concentration in blood and the effect of zinc supplementation in 11 male outpatients seropositive for human immunodeficiency virus at stage 5 according to the Walter Reed classification. Zinc concentration was measured in serum, platelets, mononuclear and polymorphonuclear cells, and erythrocytes. There was a significant increase in serum zinc concentration after zinc administration, but the zinc level in blood cells remained unchanged. All patients showed a progressive gain in body weight and a slight elevation in levels of CD4+ cells. No adverse side-effects were noticed.
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Isa, L., Lucchini, A., Lodi, S. et al. Blood zinc status and zinc treatment in human immunodeficiency virus-infected patients. Int J Clin Lab Res 22, 45–47 (1992). https://doi.org/10.1007/BF02591393
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DOI: https://doi.org/10.1007/BF02591393