Summary
An interface which permits both gradient elution capillary electrochromatography (CEC) and the coupling of high performance liquid chromatography (HPLC) to CEC is described. Mobile phase from an HPLC system with continuously variable composition is supplied on demand to the inlet of a CEC column, without the posibility of pressure driven flow. The interface also allows fractions separated by either reverse phase or normal phase HPLC to be transferred to a CEC column operated in reverse phase mode for further separation.
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Robson, M.M., Bartle, K.D. & Myers, P. Simple interface for gradient elution CEC and coupled HPLC-CEC. Chromatographia 50, 711–715 (1999). https://doi.org/10.1007/BF02497309
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DOI: https://doi.org/10.1007/BF02497309