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Physicochemical properties of membranes and functional status of liver mitochondria in rats with an inherited capacity for increased radical formation

  • Biophysics and Biochemistry
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Liver mitochondria of inbred W/SSM rats with inherited increased radical formation reveal the following anomalies: inhibition of oxidative phosphorylation, a lowered transmembrane potential, and alterations in protein-lipid interaction. The membrane viscosity and osmotic stability of mitochondria are unaffected.

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Authors and Affiliations

  1. Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk

    R. I. Salganik, I. G. Shabalina, N. G. Kolosova, V. N. Solov'ev, N. A. Solov'eva & A. R. Kolpakov

  2. Institute of Biochemistry; Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk

    R. I. Salganik, I. G. Shabalina, N. G. Kolosova, V. N. Solov'ev, N. A. Solov'eva & A. R. Kolpakov

Authors
  1. R. I. Salganik
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  2. I. G. Shabalina
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  3. N. G. Kolosova
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  4. V. N. Solov'ev
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  5. N. A. Solov'eva
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  6. A. R. Kolpakov
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, No 6, pp. 628–631, June, 1995

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Salganik, R.I., Shabalina, I.G., Kolosova, N.G. et al. Physicochemical properties of membranes and functional status of liver mitochondria in rats with an inherited capacity for increased radical formation. Bull Exp Biol Med 119, 605–607 (1995). https://doi.org/10.1007/BF02443701

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  • DOI: https://doi.org/10.1007/BF02443701

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