Abstract
The Infantile Spasms Syndrome is a fairly common form of seizures in infancy. Many papers and several books have been published on this syndrome but several aspects are still obscure. In particular, there is some controversy about anticonvulsant treatments and on the question of improvements in mental status. An unusual case of 2 monozygotic twins with by this syndrome, both with clinical manifestations appearing within a few hours on the same day, at 6 months has been followed up for 7 years, giving us the opportunity to understand some aspects of the clinical course of the disease and long term treatment.
Sommario
La sindrome dello spasmo infantile è la più frequente forma di epilessia nell'infanzia e molti lavori sono stati pubblicati sull'argomento, ma molti aspetti della sindrome sono ancora non chiariti. In particolare vi è ancora qualche controversia sulla efficacia dei trattamenti anticonvulsivanti e sul ritardo mentale. Un caso eccezionale di 2 gemelli monozigoti affetti da questa sindrome, ambedue con manifestazioni cliniche apparse a 6 mesi di età a poche ore di intervallo nello stesso giorno e seguiti poi per 7 anni ci permettono di chiarire alcuni aspetti del decorso clinico di questa malattia e del suo trattamento a lungo termine.
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Pavone, L., Mollica, F., Incorpora, G. et al. Infantile spasms syndrome in monozygotic twins. A 7-year follow-up. Ital J Neuro Sci 6, 503–506 (1985). https://doi.org/10.1007/BF02331045
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DOI: https://doi.org/10.1007/BF02331045