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Digoxin toxicity in a premature infant: Treatment with Fab fragments of digoxin-specific antibodies

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Summary

The first use of Fab fragments to treat digoxin toxicity in a premature infant with renal failure, 18 h after the onset of severe arrhythmias, is reported with dramatic results. The development of digoxin toxicity in the context of accepted therapeutic dosing to treat heart failure due to a cerebral arteriovenous malformation is discussed.

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Presti, S., Friedman, D., Saslow, J. et al. Digoxin toxicity in a premature infant: Treatment with Fab fragments of digoxin-specific antibodies. Pediatr Cardiol 6, 91–93 (1985). https://doi.org/10.1007/BF02282744

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  • DOI: https://doi.org/10.1007/BF02282744

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