Summary
The association of systemic lupus erythematosus (SLE) with amyloidosis is exceptional. We present a 37-year-old patient who was diagnosed five months earlier for SLE. She developed an acute episode of chest pain, cough and dyspnoea. Hypoxemia and obstructive changes in respiratory tests were present. The chest X-ray was repeatedly normal. Open lung biopsy revealed lupus pneumonitis with positive stain for immunoglobulins and complement, bronchiolitis obliterans, and pulmonary amyloidosis.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Wiedemann, H.P., Matthay, R.A. Pulmonary manifestations of the collagen vascular diseases. Clin Chest Med 1989, 10, 677–722.
Kinney, W.W., Angelillo, V.A. Bronchiolitis in systemic lupus erythematosus. Chest 1982, 82, 646–649.
Webb, S., Segura, F., Cervantes, F. et al. Systemic lupus erythematosus and amyloidosis. Arthritis Rheum 1979, 22, 554–556.
Ridley, M.G., Maddison, P.J., Tribe, C.R. Amyloidosis and systemic lupus erythematosus. Ann Rheum Dis 1984, 43, 649–650.
Nomura, S., Kumagai, N., Uchino, H., et al. Pulmonary amyloidosis associated with systemic lupus erythematosus. Arthritis Rheum 1986, 29, 680–682.
Matthay, R.A., Schwarz, M.I., Petty, T.L., et al. Pulmonary manifestations of systemic lupus erythematosus: Review of twelve cases of acute lupus pneumonitis. Medicine (Baltimore) 1974, 54, 397–409.
Haupt, H.M., Moore, G.W., Hutchins, G.M. The lung in systemic lupus erythematosus: Analysis of the pathologic changes in 120 patients. Am J Med 1981, 71, 791–798.
Isbister, J.P., Ralston, M., Hayes, J.M., et al. Fulminant lupus pneumonitis with acute renal failure and RBC aplasia: Successful management with plasmapheresis and immunosuppression. Arch Int Med 1981, 141, 1081–1083.
Millman, R.B., Cohen, T.B., Levinson, A.I. et al. Systemic lupus erythematosus complicated by acute pulmonary hemorrage: Recovery following plasmapheresis and cytotoxic therapy. J Rheumatol 1981, 8, 1021–1023.
Chan, C.N., Li, E., Lai, F.M. et al. An unusual case of systemic lupus erythematosus with isolated hypoglossal nerve palsy, fulminant acute pneumonitis and pulmonary amyloidosis. Ann Rheum Dis 1989, 48, 236–239.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Marenco, J.L., Sanchez-Burson, J., Ruiz Campos, J. et al. Pulmonary amyloidosis and unusual lung involvement in SLE. Clin Rheumatol 13, 525–527 (1994). https://doi.org/10.1007/BF02242957
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02242957