Summary
Isolated renal infection byMucor spp. occurs very rarely, even in the immunocompromised host. The mortality of the different forms of mucormycosis reaches 75–100% in most series. Infection of the kidney is usually diagnosed post-mortem. Thus, when renal infection is recognized, aggressive treatment including surgery and amphotericin B is required. We present a case in which a massive left renal infarction was the unique manifestation of mucormycosis in an AIDS patient. Administration of amphotericin B and left nephrectomy were necessary to achieve satisfactory outcome.
Zusammenfassung
Isolierte Mucor-Infektionen der Niere sind auch bei abwehrgeschwächten Patienten eine Seltenheit. In den meisten Serien liegt die Letalität der verschiedenen Formen der Mucormykose bei 75 bis 100%. Meist wird die Infektion der Niere erst autoptisch diagnostiziert. Die Mucormykose der Niere erfordert eine aggressive Therapie mit Operation und Amphotericin B-Behandlung. Wir stellen einen AIDS-Kranken vor, bei dem sich die Mucormykose nur an der Niere manifestierte. Durch operative Entfernung der linken Niere und Behandlung mit Amphotericin B konnte ein zufriedenstellendes Ergebnis erzielt werden.
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References
Raghavan, R., Date, A., Bhaktaviziam, A. Fungal and nocardial infections of the kidney. Histopathology 11 (1987) 9–20.
Hawkins, C., Armstrong, D. Fungal infections in the immunocompromised host. Clin. Haematol. 13 (1984) 599–630.
Flood, H. D., O'Brien, A. M., Kelly, D. G. Isolated renal mucormycosis. Postgrad. Med. J. 61 (1985) 175–176.
Berenguer, J., Solera, J., Moreno, S., Muñoz, P., Parras, F. Mucormicosis. El espectro de la enfermedad en 13 pacientes. Med. Clin. (Barcelona) 94 (1990) 766–772.
Kolbeck, P. C., Makhoul, R. G., Bollinger, R. R., Sanfilippo, F. Widely disseminatedCunninghamella mucormycosis in an adult renal transplant patient: case report and review of the literature. Am. J. Clin. Pathol. 83 (1985) 747–753.
West, B. C., Kwon-Chung, K. J., King, J. W., Grafton, W. D., Rohr, M. S. Inguinal abscess caused byRhizopus rhizopodiformis: successful treatment with surgery and amphotericin B. J. Clin. Microbiol. 18 (1983) 1384–1387.
Del Real, O., Zamora, J., Abud, C., Sada, E., Ponce de León, S., Ruiz-Palacios, G. Mucormicosis. Informe de 14 casos. Rev. Invest. Clin. 35 (1983) 237–240.
Ferry, A. P., Abedi, S. Diagnosis and management of rhinoorbitocerebral mucormycosis (phycomycosis). A report of 16 personally observed cases. Ophthalmology 90 (1983) 1096–1104.
Stave, G. M., Heimberger, T., Kerkering, T. M. Zygomycosis of the basal ganglia in intravenous drug users. Am. J. Med. 86 (1989) 115–117.
Clark, R., Greer, D. L., Carlisle, T., Carroll, B. Cutaneous zygomycosis in a diabetic HTLV-I seropositive man. J. Am. Acad. Dermatol. 22 (1990) 956–959.
Davila, R. M., Moser, S. A., Grosso, L. E. Renal mucormycosis: a case report and review of the literature. J. Urol. 145 (1991) 1242–1244.
Haseman, M. K., Blake, K., McDougall, I. R. Indium 111 WBC scan in local and systemic fungal infections. Arch. Intern. Med. 144 (1984) 1462–1463.
Clemente, C. Tratamiento actual de las micosis sistémicas. Med. Clin. (Barcelona) 81 (1983) 589–594.
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Vesa, J., Bielsa, O., Arango, O. et al. Massive renal infarction due to mucormycosis in an AIDS patient. Infection 20, 234–236 (1992). https://doi.org/10.1007/BF02033068
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DOI: https://doi.org/10.1007/BF02033068