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Lesions in the substantia nigra of rats induce thermoregulatory deficit in the cold

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Summary

Rats with either electrolytic or chemical (6-hydroxydopamine) lesions in the substantia nigra displayed decreased metabolism and hypothermia when they were exposed to cold (8 °C Ta), although they showed no deficiency in thermoregulation at both moderate (22 °C) and hot (30 °C) environmental temperatures.

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Authors and Affiliations

  1. Department of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan

    M. T. Lin, A. Chandra & Y. M. Chen

Authors
  1. M. T. Lin
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  2. A. Chandra
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  3. Y. M. Chen
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Additional information

This work was supported by grants from the Pjing-Ling Neurological Foundation (Veterans General Hospital, Taipei, Taiwan, China) and the National Science Council (Republic of China). The authors are grateful to Mr C.C. Wei for his generous support.

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Lin, M.T., Chandra, A. & Chen, Y.M. Lesions in the substantia nigra of rats induce thermoregulatory deficit in the cold. Experientia 37, 284–286 (1981). https://doi.org/10.1007/BF01991657

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