Summary
We studied the distribution of an immunoreactive substance resembling growth hormone-releasing factor (GRF) in the hypothalamus and pituitary gland of the rainbow trout by immunofluorescence methods. The GRF-like immunoreactive perikaryon was observed in colchicine-treated fish. The majority of GRF-containing neurons were located in the nucleus lateral tuberis; others were located in the caudal part of the preoptic nucleus of the hypothalamus. The GRF-like immunoreactive neuronal processes projected into the pars distalis via the pars nervosa of the pituitary gland. The distribution of the GRF-like immunoreactive substance in the hypothalamus and pituitary gland suggests that GRF plays a physiological role in the regulation of growth hormone release from the pituitary gland of rainbow trout, as it does in mammals.
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Luo, D., McKeown, B.A. Immunohistochemical detection of a substance resembling growth hormone-releasing factor in the brain of the rainbow trout (Salmo gairdneri). Experientia 45, 577–580 (1989). https://doi.org/10.1007/BF01990512
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DOI: https://doi.org/10.1007/BF01990512