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Relevance of chlorine-substituent for the antifungal activity of syringomycin and syringotoxin, metabolites of the phytopathogenic bacteriumPseudomonas syringae pv.syringae

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Abstract

Structural analogues of syringomycin and syringotoxin were produced by fermentation, characterized by FAB-MS and amino acid analysis and compared to the parent compounds in the antibiosis test againstRhodotorula pilimanae. The C-terminal residue was shown to be important for the activity.

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Authors and Affiliations

  1. Dipartimento di Scienze Biochimiche ‘A. Rossi-Fanelli’, Università ‘La Sapienza’ di Roma, I-00185, Rome

    I. Grgurina, A. Barca, S. Cervigni & A. Scaloni

  2. Dipartimento di Biochimica e di Biotecnologie Mediche, Università Federico II, I-80134, Naples

    M. Gallo

  3. Dipartimento di Chimica Organica e Biologica, Università Federico II, I-80134, Naples, Italy

    P. Pucci

Authors
  1. I. Grgurina
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  2. A. Barca
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  3. S. Cervigni
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  4. M. Gallo
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  5. A. Scaloni
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  6. P. Pucci
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Grgurina, I., Barca, A., Cervigni, S. et al. Relevance of chlorine-substituent for the antifungal activity of syringomycin and syringotoxin, metabolites of the phytopathogenic bacteriumPseudomonas syringae pv.syringae. Experientia 50, 130–133 (1994). https://doi.org/10.1007/BF01984950

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  • DOI: https://doi.org/10.1007/BF01984950

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