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Effects of a bovine pineal peptidic fraction (E5) on plasma and pituitary levels of LH, FSH and prolactin

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  • Endocrinologica
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Summary

Pituitary levels of prolactin were significantly diminished after 5 s.c. injections spaced 12 h apart of 5 μg of a partially purified bovine pineal peptide fraction (E5) in both intact and castrated rats. E5 treatment did not significantly affect the castration-induced changes in plasma luteinizing hormone (LH), follicle-stimulating hormone (FSH) or pituitary LH but did partially block the pituitary fall in FSH in castrated animals.

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References

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Author notes

  1. P. Pevet

    Present address: The Netherlands Institute for Brain Research, Amsterdam, The Netherlands

  2. C. Neascu

    Present address: Oncological Institute, Bucharest, Romania

Authors and Affiliations

  1. Department of Anatomy, The University of Texas Health Science Center at San Antonio, 78284, San Antonio, Texas, USA

    Mary K. Vaughan, B. A. Richardson (B.A.R. is a NIH Postdoctoral Fellow 1F32 NDO5900), L. Y. Johnson, R. J. Reiter, P. Pevet & C. Neascu

  2. The Netherlands Institute for Brain Research, Amsterdam, The Netherlands

    Mary K. Vaughan, B. A. Richardson (B.A.R. is a NIH Postdoctoral Fellow 1F32 NDO5900), L. Y. Johnson, R. J. Reiter, P. Pevet & C. Neascu

  3. Oncological Institute, Bucharest, Romania

    Mary K. Vaughan, B. A. Richardson (B.A.R. is a NIH Postdoctoral Fellow 1F32 NDO5900), L. Y. Johnson, R. J. Reiter, P. Pevet & C. Neascu

Authors
  1. Mary K. Vaughan
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  2. B. A. Richardson
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  3. L. Y. Johnson
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  4. R. J. Reiter
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  5. P. Pevet
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  6. C. Neascu
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Additional information

Supported by NSF grant PCM 8003441 and NIH Center for Reproductive Biology (Bioassay Core) No.P30 HD 10202. Many thanks are due A. Moreno for his excellent technical assistance.

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Vaughan, M.K., Richardson, B.A., Johnson, L.Y. et al. Effects of a bovine pineal peptidic fraction (E5) on plasma and pituitary levels of LH, FSH and prolactin. Experientia 38, 871–872 (1982). https://doi.org/10.1007/BF01972326

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  • DOI: https://doi.org/10.1007/BF01972326

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