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Methyl methane sulfonate induced enhancement of Friend viral leukemogenesis

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Summary

Exposure to the chemical carcinogen, methyl methane sulfonate, enhanced leukemogenesis in mice given threshold doses of Friend leukemia virus, as shown by peripheral white blood cell counts, splenomegaly and survival.

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Literature

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Authors and Affiliations

  1. Experimental Hematology Section, Cancer Research Unit, Clinical Radiation Therapy Research Center, Allegheny General Hospital, 15212, Pittsburgh, PA, USA

    R. B. Raikow, J. P. OKunewick, R. F. Meredith, A. E. Sheib, B. J. Brozovich & P. R. Seeman

Authors
  1. R. B. Raikow
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  2. J. P. OKunewick
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  3. R. F. Meredith
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  4. A. E. Sheib
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  5. B. J. Brozovich
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  6. P. R. Seeman
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Additional information

This work was supported by D.O.E. Contract No. EP-78-S-02-4800.A001.

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Raikow, R.B., OKunewick, J.P., Meredith, R.F. et al. Methyl methane sulfonate induced enhancement of Friend viral leukemogenesis. Experientia 36, 337–338 (1980). https://doi.org/10.1007/BF01952311

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  • DOI: https://doi.org/10.1007/BF01952311

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