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Studies on benzene mutagenesis. I. The micronucleus test

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Summary

The mutagenic action of benzene was studied by means of the micronucleus test performed on mice. A linear dose effect relationship was found for the percentage of micronucleated erythrocytes, against the benzene-dose logarithms. A significant dose effect correlation was found either after the standard 30-h experiments or after a prolonged 54-h one. A higher effect was found in the prolonged experiments, suggesting the induction of a delay in the cell cycle by benzene.

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Authors and Affiliations

  1. Fundación de Genética Humana, Salta 661/67, 1074, Buenos Aires, Argentina

    M. Diaz, Ana Reiser, L. Braier & J. Diez

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  1. M. Diaz
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  2. Ana Reiser
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  3. L. Braier
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  4. J. Diez
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Diaz, M., Reiser, A., Braier, L. et al. Studies on benzene mutagenesis. I. The micronucleus test. Experientia 36, 297–299 (1980). https://doi.org/10.1007/BF01952286

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