Skip to main content
SpringerLink
Log in

The structures of isofusicoccin and allofusicoccin

  • Published:
Experientia Aims and scope Submit manuscript

Riassunto

L'allofusicoccina e l'isofusicoccina, due isomeri della fusicoccina isolati dai brodi di coltura diFusicoccum amygdali Del., differiscono dalla fusicoccina solamente per la posizione del gruppo acetossilico sul residuo del glucosio; nella prima questo è sul C-2′ e nella seconda sul C-4′. Fusicoccina, allofusicoccina e isofusicocina, nonchè i loro 19-deacetilderivati ed i sei corrispondenti diidroderivati, si interconvertono a pH leggermente alcalino a temperatura ambiente.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. A. Ballio, E. B. Chain, P. de Leo, B. F. Erlanger, M. Mauri andA. Tonolo, Nature, Lond.203, 297 (1964).

    Article  CAS  Google Scholar 

  2. A. Ballio, M. Brufani, C. G. Casinovi, S. Cerrini, W. Fedeli, R. Pellicciari, B. Santurbano andA. Vaciago, Experientia24, 631 (1968).

    Article  CAS  PubMed  Google Scholar 

  3. K. D. Barrow, D. H. R. Barton, SirErnst Chain, U. F. W. Ohnsorge andR. Thomas, J. chem. Soc. (C),1971, 1265.

  4. A. Graniti, Phytopath. Medit.3, 125 (1964).

    CAS  Google Scholar 

  5. A. Ballio, C. G. Casinovi, G. Randazzo andC. Rossi, Experientia26, 349 (1970).

    Article  CAS  PubMed  Google Scholar 

  6. A. Ballio, A. Carilli, B. Santurbano andL. Tuttobello, Ann. Ist. Sup. di Sanita4, 317 (1968).

    CAS  Google Scholar 

  7. Similar results have been recently reported byBarrow et al.8.

  8. K. D. Barrow, D. H. R. Barton, SirErnst Chain, C. Conlay, T. C. Smale, R. Thomas andE. S. Waight, J. chem. Soc. (C),1971, 1259.

  9. UV-spectra were recorded on ethanolic solutions with a Beckman DK-2 spectrophotometer: all compounds showed only final absorption. IR-spectra were recorded in KBr pellets with a Beckman IR-9 spectrophotometer. NMR-spectra were recorded on a Varian HA-100 apparatus (unless otherwise stated) with TMS as an internal reference. Optical rotations were measured with a Perkin Elmer 141 polarimeter on ethanolic solutions. Mass spectra were recorded on an A. E. I. MS-902 spectrometer. Melting points are uncorrected. All compounds gave satisfactory elementary analyses.

  10. We are grateful to Dr.L. Paolillo for the 220 MHz spectra of fusicoccin and isofusicoccin.

  11. A. Ballio, A. Bottalico, M. Framondino, A. Graniti andG. Randazzo, Phytopath. Medit.10, 26 (1971).

    CAS  Google Scholar 

  12. A. Ballio, C. G. Casinovi, M. Framondino, G. Grandolini, G. Randazzo andC. Rossi, to be published.

  13. Like fusicoccin2,3, compound VIII gave also transacetylation ions atm/e 680 and 722.

  14. C. G. Casinovi, M. Framondino, G. Randazzo andF. Siani, to be published.

  15. This work was supported in part by the Italian Research Council (CNR). The technical assistance of Drs.F. Maietta andM. Scotto Lavinia is gratefully acknowledged.

Download references

Author information

Author notes

  1. G. Grandolini

    Present address: Istituto di Chimica Farmaceutica e Tossicologica, University of Perugia, Perugia, Italy

  2. C. Rossi

    Present address: Istituto di Tecnica e Legislazione Farmaceutica, University of Perugia, Perugia, Italy

Authors and Affiliations

  1. Laboratorio di Chimica delle Sostanze Naturali, Istituto Chimico dell'Università di Napoli, Napoli, Italy

    A. Ballio, C. G. Casinovi, M. Framondino, G. Grandolini, F. Menichini, G. Randazzo & C. Rossi

  2. Laboratori di Chimica Biologica, Istituto Superiore di Sanità, Roma, Italy

    A. Ballio, C. G. Casinovi, M. Framondino, G. Grandolini, F. Menichini, G. Randazzo & C. Rossi

Authors
  1. A. Ballio
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. C. G. Casinovi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. Framondino
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. G. Grandolini
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. F. Menichini
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. G. Randazzo
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. C. Rossi
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ballio, A., Casinovi, C.G., Framondino, M. et al. The structures of isofusicoccin and allofusicoccin. Experientia 28, 126–127 (1972). https://doi.org/10.1007/BF01935707

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01935707

Keywords

Search

Navigation