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Activation ofα-carbons of amides

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Summary

The reactions of Vilsmeir complexes of amides/imides with electrophiles afford the corresponding α-substituted products in good yield.

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References

  1. Atta-ur-Rahman, Anwer Basha, N. Waheed andS. Ahmed, Tetrahedron Lett. (1976), 219.

  2. A. Basha andAtta-ur-Rahman, Experientia, in press.

  3. O. Martensson andE. Nilsson, Acta chem. scand.14, 1129, (1960), and15, 1026 (1961).

    Article  CAS  Google Scholar 

  4. M. Brenner andH. R. Rickenbacker, Helv. chim. Acta41, 181 (1958).

    Article  CAS  Google Scholar 

  5. P. Gassman andH. R. Fox, J. org. Chem.31, 982 (1966).

    Article  CAS  Google Scholar 

  6. H. L. Needles andR. E. Whitfield, J. org. Chem.31, 989 (1966).

    Article  CAS  Google Scholar 

  7. D. R. Crouse andD. Seebach, Chem. Ber.101, 3113 (1968).

    Article  CAS  Google Scholar 

  8. R. L. Gay andC. R. Hauser, J. Am. chem. Soc.89, 1647 (1967).

    Article  CAS  Google Scholar 

  9. D. Elad andJ. Sinreich, Chem. Ind. (1965), 768.

  10. J. F. Folfe andT. G. Rogers, J. org. Chem.35, 3601 (1970).

    Google Scholar 

  11. T. Oishi, M. Nagai andY. Ban, Tetrahedron Lett. (1968), 491.

  12. T. Oishi, M. Nagai, Y. Ban andM. Ochiai, Tetrahedron Lett. (1968), 497.

  13. H. Meerwein, G. Hinz, P. Hofmann, E. Kroning andE. Peiel, J. prakt. Chem.147, 257 (1937).

    Article  CAS  Google Scholar 

  14. H. Meerwein, P. Borner, O. Fuchs, H. J. Sasse, H. Schrodt andJ. Spille, Chem. Ber.89, 2060 (1956).

    Article  CAS  Google Scholar 

  15. H. Meerwein, P. Laasch, R. Mersch andJ. Spille, Chem. Ber.89, 209 (1956).

    Article  CAS  Google Scholar 

  16. M. Depoortere, J. Marchand-Bryhaert andL. Ghosez, Angew. Chem., Int. edn. Eng.13, 268 (1974), and references therein.

    Article  Google Scholar 

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Atta-ur-Rahman, Basha, A. & Ahmad, V.U. Activation ofα-carbons of amides. Experientia 32, 1491–1492 (1976). https://doi.org/10.1007/BF01924410

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  • DOI: https://doi.org/10.1007/BF01924410

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