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Specific removal of DNA antibody with an immunoadsorbent

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Résumé

Une colonne immunoadsorbante d'ADN-cellulose contenu dans une matrice d'agar a servi à extraire d'une manière spécifique des anticorps sériques anti-ADN. Approximativement 70% des anticorps sériques anti-ADN ont été adsorbés durant une période de 8 h, avec une libération minime, par la colonne d'ADN marquée I125. Ces résultats permettent d'espérer une approche spécifique du traitement du lupus erythémateux disséminé.

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Literatur

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Authors and Affiliations

  1. Administration Hospital, University of Colorado Medical Cneter and Veterans, 1055 Clermont Street, 80220, Denver, Colorado, USA

    D. S. Terman, I. Stewart, Andrée Hoffmann, R. Carr & R. Harbeck

  2. National Jewish Hospital and Research Center, Denver, Colorado, USA

    D. S. Terman, I. Stewart, Andrée Hoffmann, R. Carr & R. Harbeck

Authors
  1. D. S. Terman
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  2. I. Stewart
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  3. Andrée Hoffmann
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  4. R. Carr
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  5. R. Harbeck
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Additional information

Author D.S.T. is the recipient of a V.A. Clinical Investigator Award, to whom correspondence has to be addressed. This work was supported in part by a grant from the Upjohn Pharmaceutical Company.

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Terman, D.S., Stewart, I., Hoffmann, A. et al. Specific removal of DNA antibody with an immunoadsorbent. Experientia 30, 1493–1494 (1974). https://doi.org/10.1007/BF01919715

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  • DOI: https://doi.org/10.1007/BF01919715

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