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Vergleichende Untersuchung einiger TPN-abhängiger Dehydrogenasen und anderer Serum-Enzyme bei Patienten mit progressiver Muskeldystrophie

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Zusammenfassung

Die Autoren untersuchten die Aktivität von ICDH, G-6-PDH und 6-PGDH im Plasma von zehn jungen Patienten mit Dystrophia musculorum progressiva und fanden eine signifikante Zunahme der ICDH- und 6-PGDH-Aktivität.

Die G-6-PDH-Aktivität war oft etwas erhöht, ohne daß jedoch bei der Variabilität des Verhaltens eine statistische Signifikanz erreicht wurde. Schließlich wurden im Plasma die PFK-, ENO-, FUM- und PRL-Aktivitäten untersucht, die keine Veränderungen zeigten.

Summary

The authors studied the behaviour of ICDH, G-6-PDH and 6-PGDH in the plasma from 10 young patients, suffering from progressive muscular dystrophy, showing a statistically significant increase of ICDH and 6-PGDH activity.

The G-6-PDH activity was often slightly increased, but this increase did not reach the statistical importance due to a larger variability of the phenomenon. Studies regarding PFK, ENO, FUM and PRL activities have been made in the plasma with negative results.

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Authors and Affiliations

  1. Clinica delle Malattie Infettive dell'Università di Napoli, Italy

    G. Giusti, A. Ascione & L. Cacciatore

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  1. G. Giusti
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  2. A. Ascione
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  3. L. Cacciatore
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Giusti, G., Ascione, A. & Cacciatore, L. Vergleichende Untersuchung einiger TPN-abhängiger Dehydrogenasen und anderer Serum-Enzyme bei Patienten mit progressiver Muskeldystrophie. Klin Wochenschr 45, 292–295 (1967). https://doi.org/10.1007/BF01747098

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