Summary
The case of a 56-year old woman with severe Cushing's syndrome due to ovarian ACTH-production is described. Both clinical picture and biochemical pattern were consistent with the ectopic ACTH syndrome. ACTH was found by specific immunohistochemical staining in a carcinoid tumor of the patient's right ovary. In contrast, pituitary cells exhibited immunoreactive ACTH to only a minimum extent.
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Abbreviations
- ACTH:
-
adrenocorticotropic hormone
- CT:
-
computerized tomography
- APUDoma:
-
tumor of amine precursor utake and decarboxylation cells
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Schlaghecke, R., Kreuzpaintner, G., Bürrig, K.F. et al. Cushing's syndrome due to ACTH-production of an ovarian carcinoid. Klin Wochenschr 67, 640–644 (1989). https://doi.org/10.1007/BF01718148
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DOI: https://doi.org/10.1007/BF01718148