Abstract
A case of an immunocompromised patient who experienced two episodes of septicemia caused by a coryneform bacterium is reported. Biochemical characteristics and analysis of cellular fatty acids and of cell wall components showed two identical strains ofBrevibacterium casei to be responsible for these infections. The lack of easy-to-perform methods for identification may have led, in the past, to an underestimation of the role of this bacterium, especially in immunocompromised patients.
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Lina B, Carlotti A, Lesaint V, Devaux Y, Freney J, Fleurette J: Persistent bacteremia due toBrevibacterium sp. in an immunocompromised patient. Clinical Infectious Diseases 1994, 18: 487–488.
Mira-Gutierez J, Rodriguez-lglesias MA: Un cas clinique d'empyème àBrevibacterium linens. Médecine et Maladies Infectieuses 1986, 16: 224–225.
Coyle MB, Lipsky BA: Coryneform bacteria in infectious diseases; clinical and laboratory aspects. Clinical Microbiological Reviews 1990, 3: 227–246.
Gruner E, Pfyffer GE, Von Graevenitz A: Characterization ofBrevibacterium spp. from clinical specimens. Journal of Clinical Microbiology 1993, 31: 1408–1412.
Neumeister B, Mandel T, Gruner E, Pfyffer GE:Brevibacterium species as a cause of osteomyelitis in a neonate. Infection 1993, 21: 177–178.
Funke G, Carlotti A: Differentiation ofBrevibacterium spp. encountered in clinical specimens. Journal of Clinical Microbiology 1994, 32: 1729–1732.
Nash P, Krenz MM: Culture media. In: Balows A, Hausler WJ Jr., Herrmann KL, Isenberg HD, Shadomy HJ (ed): Manual of clinical microbiology. American Society for Microbiology, Washington DC, 1991, p. 1226–1289.
Pitcher DG, Malnick H: Identification ofBrevibacterium from clinical sources. Journal of Clinical Pathology 1984, 37: 1395–1398.
Von Graevenitz A, Osterhout G, Dick J: Grouping of some clinically relevant gram-positive rods by automated fatty acid analysis. APMIS 1991, 99: 147–154.
Schaal KP: Identification of significant actinomycetes and related bacteria using chemical techniques. In: Goodfellow M, Minnikin DE (ed): Chemical methods in bacterial systematics. Academic, London, 1985, p. 359–381.
National Committee for Clinical Laboratory Standards: Performance standards for antimicrobial susceptibility testing, Approved standard M100-S5. NCCLS, Villanova, PA, 1994.
Gruner E, Steigerwalt AG, Hollis DG, Weyant RS, Weaver RE, Moss CW, Daneshvar MD, Brown JM, Brenner DJ: Human infections caused byBrevibacterium casei, formerly CDC groups B-1 and B-3. Journal of Clinical Microbiology 1994, 32: 1511–1518.
Bernard KA, Bellefeuille M, Evan EP: Cellular fatty acid composition as an adjunct to the identification of asporogenous aerobic gram positive rods. Journal of Clinical Microbiology 1991, 29: 83–89.
Carlotti A, Meugnier H, Pommier MT, Villard J, Freney J: Chemotaxonomy and molecular taxonomy of some coryneform clinical isolates. Zentralblatt für Bakteriologie 1993, 278: 23–33.
Jones D, Keddie RM: Irregular, nonsporing gram-positive rods. In: Sneath PHA, Mair NS, Sharpe ME, Holt JG: Bergey's manual of systemic bacteriology. Williams & Wilkins, Baltimore, 1986, p. 1261–1266.
McCaughey C, Damani NN: Central venous line infection caused byBrevibacterium epidermidis. Journal of Infection 1991, 23: 211–212.
McBride ME, Ellner KM, Black HS, Clarridge JE, Wolf JE: A newBrevibacterium sp. isolated from infected genital hair of patients with white piedra. Journal of Medical Microbiology 1993, 39: 255–261.
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Reinert, R.R., Schnitzler, N., Haase, G. et al. Recurrent bacteremia due toBrevibacterium casei in an immunocompromised patient. Eur. J. Clin. Microbiol. Infect. Dis. 14, 1082–1085 (1995). https://doi.org/10.1007/BF01590943
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DOI: https://doi.org/10.1007/BF01590943