Summary
Infection of SJL/J mice with the lactate dehydrogenase virus resulted in a greater increase in the plasma activities of lactate dehydrogenase, malate dehydrogenase, and isocitrate dehydrogenase than expected from findings with other inbred strains. Evidence is presented to suggest that the differences are due to an exaggerated reduction in the clearance of these enzymes. It is postulated that the data signify a deficiency in the function of the reticuloendothelial system of SJL/J mice.
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This work was partially supported by Institutional Research Grant, IN-66, American Cancer Society, to the University of Alabama in Birmingham.
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Crispens, C.G. Studies on the response of SJL/J mice to infection with the lactate dehydrogenase virus. Archiv f Virusforschung 35, 177–182 (1971). https://doi.org/10.1007/BF01249708
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DOI: https://doi.org/10.1007/BF01249708