Skip to main content
SpringerLink
Log in

The in vitro stability of doxifluridine in whole blood and plasma

  • Letters To The Editors
  • Published:
European Journal of Clinical Pharmacology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Schaaf L, Dobbs B, Edwards IR, Perrier D (1987) Nonlinear pharmacokinetic characteristics of 5-fluorouracil (5-FU) in colorectal cancer patients. Eur J Clin Pharmacol 32: 411–418

    Google Scholar 

  2. Schaaf L, Ferry D, Hung C, Perrier D, Edwards IR (1985) Analysis of 5′-deoxy-5-fluorouridine and 5-fluorouracil in human plasma and urine by high-performance liquid chromatography. J Chromatogr 342: 303–313

    Google Scholar 

  3. Schaaf L, Dobbs B, Edwards IR, Perrier D (1988) Pharmacokinetics of doxifluridine and 5-fluorouracil after single intravenous infusions of doxifluridine to patients with colorectal cancer. Eur J Clin Pharmacol 34: 439–443

    Google Scholar 

  4. Gibaldi M, Perrier D (1982) Nonlinear pharmacokinetics. In: Swarbrick J (ed) Pharmacokinetics, 2nd edn. Marcel Dekker, New York, pp 271–318

    Google Scholar 

  5. de Bruijn E, van Oosterom A, Tjaden U, Reeuwijk H, Pinedo H (1985) Pharmacology of 5′-deoxy-5-fluorouridine in patients with resistant ovarian cancer. Cancer Res 45: 5931–5935

    Google Scholar 

  6. Diem K, Lentner C (eds) (1970) In: Documenta Geigy, 7th edn. Basle, Ciba Geigy Ltd. Basle, Switzerland

    Google Scholar 

Download references

Author information

Author notes

  1. L. J. Schaaf

    Present address: Department of Pharmaceutical Sciences, University of Nebraska Medical Center, College of Pharmacy, Omaha, Nebraska

  2. D. G. Perrier

    Present address: Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada

Authors and Affiliations

  1. Department of Pharmacy, University of Otago Medical School, Dunedin, New Zealand

    L. J. Schaaf & D. G. Perrier

  2. Medical Research Council of New Zealand, Toxicology Research Unit, University of Otago Medical School, Dunedin, New Zealand

    B. R. Dobbs & I. R. Edwards

Authors
  1. L. J. Schaaf
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. B. R. Dobbs
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. I. R. Edwards
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. D. G. Perrier
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Schaaf, L.J., Dobbs, B.R., Edwards, I.R. et al. The in vitro stability of doxifluridine in whole blood and plasma. Eur J Clin Pharmacol 34, 533–534 (1988). https://doi.org/10.1007/BF01046718

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01046718

Key words

Search

Navigation