Abstract
Potential chelating-forming ligands and reagents for heterocyclization — ethyl esters of 4-[N-(R-pyrid-2-yl)carbamoyl]-3-amino-2-cyanobuten-2-oic acids ["codimers" of cyanoacetic acid ethyl ester (EECA) and the corresponding (pyrid-2-yl) amides of this same acid) — were synthesized in two ways: by condensation of 2-dialkylborylamidopyridines (picolines) with EECA (via chelate compounds of boron) and by the reaction of EECA dimer with 2-aminopyridines (picolines).
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N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, 117913 Moscow. Translated from Izvestiya Akademii Nauk, Seriya Khimicheskaya, No. 2, pp. 371–376, February, 1992.
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Dorokhov, V.A., Baranin, S.V., Dib, A. et al. "Codimers" of N-(pyrid-2-yl) amides and ethyl cyanoacetate. Russ Chem Bull 41, 287–291 (1992). https://doi.org/10.1007/BF00869516
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DOI: https://doi.org/10.1007/BF00869516