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Multiple symmetrical lipomatosis in the neck

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Summary

Multiple symmetrical lipomatosis (Madelung's disease) is a very rare condition that is commonest in countries bordering the Mediterranean. The disease is associated with symmetrical unencapsulated fat deposits over the neck and upper trunk. We present the first reported occurrence in the Chinese. Although lesions can initially mimic a head and neck malignancy, management is essentially symptomatic, with conservative removals done as indicated clinically or for cosmesis.

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References

  1. Brodie BC (1846) Lectures illustrative of various subjects in pathology and surgery. Longman, London, pp 275–276

    Google Scholar 

  2. Carlin MC, Ratz JL (1988) Multiple symmetric lipomatosis: treatment with liposuction. J Am Acad Dermatol 18:359–362

    Google Scholar 

  3. Enzi G, Inelmen EM, Baritussio A (1977) Multiple symmetric lipomatosis: a defect in adrenergic-stimulated lipolysis. J Clin Invest 60:1221–1229

    Google Scholar 

  4. Herrmann WP, Aulepp H, Huffman G (1978) Lipomatosis symmetrica benigna mit Hyperlipoproteinämie Typ IV and Epipharynx-Karzinom. Z Hautkr 53:580–586

    Google Scholar 

  5. Leung NWY, Gaer J (1987) Multiple symmetric lipomatosis (Launois-Bensaude syndrome): effect of oral salbutamol. Clin Endocrinol 7:601–606

    Google Scholar 

  6. Madelung OW (1888) Ueber den Fetthals (diffuses Lipom des Halses). Arch Klin Chir 37:106–130

    Google Scholar 

  7. McKusick VA (1978) Mendelian inheritance in man. Johns Hopkins University, Baltimore, p 242

    Google Scholar 

  8. Moretti JA, Miller D (1973) Laryngeal involvement in benign symmetric lipomatosis. Arch Otolaryngol 97:495–496

    Google Scholar 

  9. Pollock M, Nicholson GI, Nukada H, Cameron S (1988) Neuropathy in multiple symmetric lipomatosis, Madelung's disease. Brain 111:1157–1171

    Google Scholar 

  10. Ruzicke T, Vieluf D, Landthaler M, Braun-Falco O (1987) Benign symmetric lipomatosis Launois-Bensaude. J Am Acad Dermatol 17:663–673

    Google Scholar 

  11. Tizian C, Berger A, Vykoupil K (1983) Malignant degeneration in Madelung's disease (benign lipomatosis of the neck): case report. Br J Plast Surg 36:187–189

    Google Scholar 

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John, D.G., Fung, H.K., van Hasselt, C.A. et al. Multiple symmetrical lipomatosis in the neck. Eur Arch Otorhinolaryngol 249, 277–278 (1992). https://doi.org/10.1007/BF00714492

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  • DOI: https://doi.org/10.1007/BF00714492

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