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The prophylactic use of phenytoin during iopamidol contrast studies of the subarachnoid space

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Summary

Contrast examinations of the subarachnoid space are associated with side effects including convulsions. Attention has been given to the prophylactic use of anticonvulsants. We describe a simple oral regimen using the established anticonvulsant phenytoin that can be administered to short-stay patients and that achieves effective serum and CSF concentrations.

A preliminary account of this work was presented to the British Pharmacological Society in January 1984 in London.

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Authors and Affiliations

  1. Departments of Materia Medica and Pharmacy, Stobhill General Hospital, Glasgow, UK

    P. J. de Vane, M. Casey, J. C. Kelly & B. Whiting

  2. Department of Neuroradiology, Institute of Neurological Sciences, Southern General Hospital, Glasgow, UK

    P. Macpherson, E. Teasdale & G. Volo

Authors
  1. P. J. de Vane
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  2. P. Macpherson
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  3. E. Teasdale
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  4. G. Volo
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  5. M. Casey
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  6. J. C. Kelly
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  7. B. Whiting
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de Vane, P.J., Macpherson, P., Teasdale, E. et al. The prophylactic use of phenytoin during iopamidol contrast studies of the subarachnoid space. Eur J Clin Pharmacol 29, 747–749 (1986). https://doi.org/10.1007/BF00615973

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  • DOI: https://doi.org/10.1007/BF00615973

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