Abstract
The surface cells (SEC) luminal membrane conductance to Cl− was tested on the resting Necturus gastric mucosa by applying conventional and Cl−-sensitive microelectrodes under luminal low-Cl− conditions. Reduction of chloride (2 mmol/l) in the luminal bath did not result in any detectable reduction of intracellular Cl−. Therefore, in analogy to previous findings on the frog SEC, also the luminal membrane of the Necturus surface cells appears to have a negligible conductance to Cl−. The data speak against a relevant role of the amphibian SEC in the non-acidic Cl− secretion.
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References
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Schettino, T., Curci, S. On the luminal membrane permeability to Cl− of necturus gastric surface cells. Pflugers Arch. 403, 331–333 (1985). https://doi.org/10.1007/BF00583610
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DOI: https://doi.org/10.1007/BF00583610