Summary
The livers of 26 adult male and female trout were studied histochemically. G6Pase activity was always found to be heterotopically distributed with a constant maximum in the periportal area. In many cases the glycogen content and the activity of phosphorylase predominated in the periportal zone as well. Maximum activity of glucose-6-phosphate-dehydrogenase and malic enzyme, however, could be demonstrated preferentially in the perivenous area. Lactate dehydrogenase, succinate dehydrogenase, alcohol dehydrogenase, acid phosphatase and β-glucuronidase were found equally in all liver cells. 3-Hydroxybutyrate dehydrogenase was absent. Thus, the principles of metabolic zonation have been established in trout liver, the architecture of which differs essentially from that of mammals. The course of the terminal afferent and efferent vessels is the decisive factor for the heterotopic localization of functional units rather than the tubular or plate-forming arrangement of the hepatocytes.
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Supported by Grants from the Deutsche Forschungsgemeinschaft (Sa 127/8-4)
Parts of this study were presented as an Inauguraldissertation to the Medical Faculty of the University of Basel
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Schär, M., Maly, I.P. & Sasse, D. Histochemical studies on metabolic zonation of the liver in the trout (Salmo gairdneri). Histochemistry 83, 147–151 (1985). https://doi.org/10.1007/BF00495145
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DOI: https://doi.org/10.1007/BF00495145