Summary
This report concerns a 17-year-old male patient with atypical mycosis fungoides (m.f.). Initial examination revealed generalized lymphoma and uncharacteristic livid skin efflorescence. The patient developed bone marrow involvement and meningeal leukaemia 6 months later. Diagnosis was confirmed by immunohistochemistry and electron microscopy. Aggressive chemotherapy yielded no response.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Alibert JLM (1806) Description des maladies de la peau; Observees a l'hospital Saint Louis, et exposition des meilleures methodes suivies pour leur traitement. Paris, Barrois L'aine et Fils:157
Bazin DA (1876) Maladies de la peau observees a l'hospital Saint Louis, Paris
Bodensteiner DC, Skikne B (1982) Central nervous system involvement in mycosis fungoides. Cancer 50:1181
Broder S, Bunn PA (1980) Cutaneous T-cell lymphomas. Semin Oncol 3:310
Clendenning WE, Brecher G, van Scott EJ (1964) Mycosis fungoides. Relationship to malignant cutaneous reticulosis and the Sézary syndrome. Arch Dermatol 89:785–792
Cohen SR, Stenn KS, Braverman IM, Beck GJ (1980) Mycosis fungoides: Clinicopathologic relationships, survival and therapy in 59 patients with observations on occupation as a new prognostic factor. Cancer 46:2654
Epstein EM, Levin DL, Croft JD, Lutzner MA (1972) Mycosis fungoides: Survival, prognostic feature response to therapy, and autopsy findings. Medicine 51:61–72
Hanch TW, Shelbourne JD, Cohen JH, et al. (1975) Meningeal mycosis fungoides: Clinical and cellular characteristics. Ann Intern Med 82:499
Heintel H, Heintel-Troster U, Worbes C (1969) Mycosis fungoides mit Beteiligung der Leptomeningen, Hirnnerven, Rückenmarkswurzeln und Spinalganglien: “Meningeosis mycoides fungosa”. Dtsch Z Nervenheilkd 196:156
Lennert K (1967) Classification of malignant lymphomas (European concept). In: Ruttimann A (ed) Progress in Lymphology, Thieme, Stuttgart, p 103
Lundberg WB, Cadman EC, Skeel RT (1976) Leptomeningeal mycosis fungoides. Cancer 38:2149
Lutzner MA, Jordan HW (1968) The ultrastructure of an abnormal cell in Sézary's syndrome. Blood 31:719
McNutt NS, Crain WR (1981) Quantitative electron microscopic comparison of lymphocyte nuclear contours in mycosis fungoides and in benign infiltrates in skin. Cancer 47:698
Rappaport H, Thomas LB (1974) Mycosis fungoides: The pathology of extracutaneous involvement. Cancer 34:1198–1229
Sézary A Bouvrain Y (1938) Erythrodermie avec presence de cellules monstruenses dans derme et sang circulant. Bull Soc Franc dermat et Syph 45:254
Taswell HF, Winkelman RK (1961) Sézary syndrome — a malignant reticulemic erythroderma. J Am Med Assoc 177:465
Vonderheid EC, van Scott EJ, Wallner PE et al. (1979) A ten year experience with topical mechlorthamine for mycosis fungoides. Cancer Treat Rep 63:681
Zucker-Franklin D (1974) Properties of the Sézary lymphoid cell: An ultrastructural analysis. Mayo Clin Proc 49:567
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Görg, C., Görg, K., Bepler, G. et al. Atypical mycosis fungoides with cerebral involvement. J Cancer Res Clin Oncol 110, 123–126 (1985). https://doi.org/10.1007/BF00402724
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00402724