References
Bishop JM (1987) The molecular genetics of cancer. Science 235: 305–311
Brash DE, Ziegler JA, Simon JA, Lin A, McKenna GJ, Baden HP, Halperin AJ, Ponten J (1991) A role for sunlight in skin cancer: UV induced p53 mutations in squamous cell carcinoma. Proc Natl Acad Sci USA 88: 10124–10128
Campbell C, Quinn AG, Ro YS, Angus B, Rees JL (1993) p53 mutations are common and early events that precede tumor invasion in squamous cell neoplasia of the skin. J Invest Dermatol 100: 746–748
Campo E, Calle-Martin O, Miquel R, Palacin A, Romero M, Fabregat V, Vives J, Cardesa A, Yague J (1993) Loss of heterozygosity of p53 gene and p53 protein expression in human colorectal carcinomas. Cancer Res 51: 4436–4442
Coles C, Condie A, Chetty U, Steel CM, Evans HJ, Presser J (1992) p53 mutations in breast cancer. Cancer Res 52: 5291–5298
Dockhorn-Dworniczack B, Yandell DW, Merritt V, Böcker W, Poremba C (1993) p53 mutation in primary malignant melanoma. In: Proceedings of the American Association for Cancer Research, vol 34, abstract 658
Hollstein M, Sidransky D, Vogelstein B, Harris CC (1991) p53 mutations in human cancers. Science 253: 49–53
Jones MH, Nakamura Y (1992) Detection of loss of heterozygosity at the human TP53 locus using a dinucleotide repeat polymorphism. Genes Chromosom Cancer 5: 89–90
Levine AJ, Momand J, Finlay CA (1991) The p53 tumor suppressor gene. Nature 351: 453–456
Malkin D, Li FP, Strong LC, Fraumeni JF, Nelson CE, Kassel J, Gryka MA, Bischoff FZ, Tainsky MA, Friend SH (1990) Germline p53 mutations in a familial syndrome of breast cancer, sarcomas and other neoplasias. Science 254: 1233–1238
Miller HJ (1985) Mutagenic specificity of ultraviolet light. J Mol Biol 182: 45–68
Nigro JM, Barker SJ, Preisinger AC, Jessup JM, Hostetter R, Cleary K, Bigner SH, Davidson N, Baylin S, Devilee P, Glover T, Collins FS, Weston A, Modali R, Harris CC Vogelstein B (1985) Mutations in the p53 gene occur in diverse human tumour types. Nature 342: 705–708
Volkenandt M, Schlegel U, Nanus DM, Albino AP (1991) Mutational analysis of the human p53 gene in malignant melanoma. Pigment Cell Res 4: 35–40
Weiss J, Schwechheimer K, Cavenee WK, Herlyn M, Arden KC (1993) Mutation and expression of the p53 gene in malignant melanoma cell lines. Int J Cancer 53: 693–699
Ziegler A, Lefell DJ, Kunala S, Sharma HW, Gailani M, Simon JA, Halparin AJ, Baden HP, Shapiro PE, Bale AE, Brash DE (1993) Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancer. Proc Natl Acad Sci USA 90: 4216–4220
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Weiss, J., Cavenee, W.K., Herbst, R.A. et al. Point mutations and allelic loss in the TP53 locus of cutaneous malignant melanomas. Arch Dermatol Res 286, 417–419 (1994). https://doi.org/10.1007/BF00371803
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DOI: https://doi.org/10.1007/BF00371803