Skip to main content
SpringerLink
Log in

A preliminary vaccine potency trial of a Newcastle Disease Virus inactivated with binary ethylenimine

  • Research Article
  • Published:
Veterinary Research Communications Aims and scope Submit manuscript

Abstract

Inactivation of Newcastle Disease Virus (NDV) by binary ethylenimine (BEI) is reported. The activity of an oil vaccine prepared with BEI-inactivated NDV was compared to a vaccine prepared with formalin-inactivated NDV.

The BEI inactivated vaccine had almost twice the efficacy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Bahnemann, H. G. 1975. Binary ethylenimine as an inactivant for foot-and-mouth disease virus and its application for vaccine production. Arch. Virol., 47, 47–56

    Google Scholar 

  • Larghi, O. P. & Nebel, A. 1980. Rabies virus inactivation by binary ethylenimine: new method for inactivated vaccine production. Journal of Clinical Microbiology, 2, 120–122

    Google Scholar 

  • Sun, I. L., Gustafson, D. P. & Scherba, G. 1978. Comparison of pseudorabies virus inactivated by bromo-ethyleneimine, coirradiation, and acridine dye in immune assay systems. Journal of Clinical Microbiology, 8, 604–611

    Google Scholar 

  • Wrathall, A. E., Wells, S. F., Cartwright, S. F. & Frerichs, G. N. 1984. An inactivated, oil-emulsion vaccine for prevention of porcine parvovirus-induced reproductive failure. Research in Veterinary Science, 36, 136–143

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratorio di Medicina Veterinaria, Istituto Superiore di Sanità, Roma, Italy

    C. Buonavoglia & M. Tollis

  2. Istituto Patologia Aviare, Università di Napoli, Italy

    A. Fioretti, F. Menna & V. Papparella

Authors
  1. C. Buonavoglia
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. Fioretti
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. Tollis
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. F. Menna
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. V. Papparella
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Buonavoglia, C., Fioretti, A., Tollis, M. et al. A preliminary vaccine potency trial of a Newcastle Disease Virus inactivated with binary ethylenimine. Veterinary Research Communications 12, 195–197 (1988). https://doi.org/10.1007/BF00362801

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00362801

Keywords

Search

Navigation