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On chiasma formation point processes having the count location property

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Abstract

The count-location (C-L) chiasma formation schemes introduced by Karlin and Liberman (1979b) encompass a broad class of map functions involving positive, negative or no chiasma interference. The C-L schemes do not explictly assume a specific mechanism of crossover formation, but rather a statistical property of the process. If viewed as a stochastic point process along the chromosome, it is shown that a crossing over mechanism having the C-L property is actually a rescaled mixture of Poisson processes. Surprisingly it turns out that these C-L point processes involve negative interference throughout the entire genome.

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Research supported in part by NIH grants GM 28016 and GM 10452

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Liberman, U. On chiasma formation point processes having the count location property. J. Math. Biology 21, 1–10 (1984). https://doi.org/10.1007/BF00275218

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  • DOI: https://doi.org/10.1007/BF00275218

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