Summary
Two types of neurons can be recognized in the region above the lateral geniculate nucleus. One cell type is found in the caudal part of the reticular nucleus of thalamus; these cells are accordingly called reticular neurons. The other cell type is located in the perigeniculate nucleus immediately above lamina A of the lateral geniculate nucleus and in the intermediate zone between the perigeniculate nucleus and the reticular nucleus. These cells are referred to as perigeniculate neurons. Electrical stimulation of the optic tract and the visual cortex typically evokes a short burst of spikes in the perigeniculate neurons, and the excitation has a shorter latency from the cortex (range 1.2–2.5 ms) than from the optic tract (range 1.5–3.1 ms). The perigeniculate neurons are also activated by adequate visual stimuli. In contrast, the reticular neurons are unresponsive to visual stimuli and electrical stimulation of the optic tract but they may respond with a burst of spikes to cortex stimulation with rather long latency (range 2.7–5.5 ms). It is concluded that only perigeniculate neurons qualify as interneurons in the recurrent inhibitory pathway to principal cells in the lateral geniculate nucleus.
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References
Ahlsén G, Lindström S (1978) Axonal branching of functionally identified neurones in the lateral geniculate body of the cat. Neurosci Lett [Suppl] 1: 156.
Ahlsén G, Lindström S (1982) Excitation of perigeniculate neurones via axonal collaterals of principal cells. Brain Res (in press).
Ahlsén G, Lindström S, Sybirska E (1978) Subcortical axon collaterals of principal cells in the lateral geniculate body of the cat. Brain Res 156: 106–109.
Ahlsén G, Grant K, Lindström S (1982) Monosynaptic excitation of principal cells in the lateral geniculate nucleus by corticofugal fibres. Brain Res (in press).
Andersen P, Andersson SA (1968) Physiological basis of the alpha rhythm. Appleton-Century-Crofts, New York.
Andersen P, Eccles JC, Sears TA (1964) The ventrobasal complex of the thalamus: Types of cells, their responses and their functional organization. J Physiol (Lond) 174: 370–399.
Bishop PO (1964) Properties of afferent synapses and sensory neurons in the lateral geniculate nucleus. Int Rev Neurobiol 6: 191–255.
Bowling DB, Michael CR (1980) Projection patterns of single physiologically characterized optic tract fibres in cat. Nature 286: 899–902.
Burke W, Sefton AJ (1966) Inhibitory mechanisms in lateral geniculate nucleus of rat. J Physiol (Lond) 187: 231–246.
Dubin MW, Cleland BG (1977) Organization of visual inputs to interneurons of lateral geniculate nucleus of the cat. J Neurophysiol 40: 410–427.
Ferster D, LeVay S (1978) The axonal arborization of lateral geniculate neurons in the striate cortex of the cat. J Comp Neurol 182: 923–944.
Gilbert CD, Kelly JP (1975) The projection of cells in different layers of the cat's visual cortex. J Comp Neurol 163: 81–106.
Hubel DH (1960) Single unit activity in lateral geniculate body and optic tract of unrestrained cats. J Physiol (Lond) 150: 91–104.
Jones EG (1975) Some aspects of the organization of the thalamic reticular complex. J Comp Neurol 162: 285–308.
Kawamura S, Sprague JM, Niimi K (1974) Corticofugal projections from the visual cortices to the thalamus, pretectum and superior colliculus in the cat. J Comp Neurol 158: 339–362.
Laties AM, Sprague JM (1966) The projection of optic fibers to the visual centers in the cat. J Comp Neurol 127: 35–70.
Lindström S (1982) Synaptic organization of inhibitory pathways to principal cells in the lateral geniculate nucleus of the cat. Brain Res (in press).
Ono T, Noell WK (1973) Characteristics of P- and I-cells of the cat's lateral geniculate body. Vision Res 13: 639–646.
Sanderson KJ (1971) The projection of the visual field to lateral geniculate and medial interlaminar nuclei in the cat. J Comp Neurol 143: 101–118.
Scheibel ME, Scheibel AB (1966) The organization of the nucleus reticularis thalami: A Golgi study. Brain Res 1: 43–62.
Scheibel ME, Scheibel AB (1967) Structural organization of nonspecific thalamic nuclei and their projection toward cortex. Brain Res 6: 60–94.
Scheibel ME, Scheibel AB (1972) Specialized organizational patterns within the nucleus reticularis thalami of the cat. Exp Neurol 34: 316–322.
Schmielau F (1979) Integration of visual and nonvisual information in nucleus reticularis thalami of the cat. In: Freeman RD (ed) Developmental neurobiology of vision. Plenum Press, New York, pp 205–226.
Singer W, Bedworth N (1973) Inhibitory interaction between X and Y units in the cat lateral geniculate nucleus. Brain Res 49: 291–307.
So YT, Shapley RM (1979) Spatial properties of X and Y cells in the lateral geniculate nucleus of the cat and conduction velocities of their inputs. Exp Brain Res 36: 533–550.
Sugitani M (1979) Electrophysiological and sensory properties of the thalamic reticular neurones related to somatic sensation in rats. J Physiol (Lond) 290: 79–95.
Sumimoto I, Nakamura M, Iwama K (1976) Location and function of the so-called interneurons of rat lateral geniculate body. Exp Neurol 51: 110–123.
Suzuki H, Kato E (1966) Binocular interaction of cat's lateral geniculate body. J Neurophysiol 29: 909–920.
Updyke BV (1975) The patterns of projection of cortical areas 17, 18, and 19 onto the laminae of the dorsal lateral geniculate nucleus in the cat. J Comp Neurol 163: 377–396.
Thuma BD (1928) Studies on the diencephalon of the cat. I. The cyto-architecture of the corpus geniculatum laterale. J Comp Neurol 46: 173–199.
Żernicki B (1968) Pretrigeminal cat. Brain Res 9: 1–14.
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Supported by Magnus Bergvalls Stiftelse and The Swedish Medical Research Council (Project no. 4767)
F.-S. Lo had an exchange fellowship from the Royal Swedish Academy of Engineering
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Ahlsén, G., Lindström, S. & Lo, F.S. Functional distinction of perigeniculate and thalamic reticular neurons in the cat. Exp Brain Res 46, 118–126 (1982). https://doi.org/10.1007/BF00238105
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DOI: https://doi.org/10.1007/BF00238105