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R-plasmids in Salmonella isolates from sporadic cases of gastroenteritis

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Abstract

Five-hundred and twenty seven strains of Salmonella isolated from different patients admitted to hospitals in Rome from 1982 to 1985 were screened for their resistance to antimicrobial drugs.

Sixty-one strains (11.6%) were found to be resistant to two or more antibiotics; the most frequent resistances were to sulfathiazole, streptomycin, tetracycline, chloramphenicol and ampicillin. Of the thirty-eight strains showing resistance to three or more antibiotics, 17 were able to transfer their resistance to E. coli K 12.

The isolates were heterogeneous in plasmid population: only few strains harbored a sole plasmid, most harbored many plasmids ranging between 20 and 120 megadaltons in weight. Most strains were found to carry a conjugative plasmid of incompatibility group Inc H of 100–120 megadaltons and Inc I α of 60–70 megadaltons.

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Filetici, E., Martini, A., Magni, L. et al. R-plasmids in Salmonella isolates from sporadic cases of gastroenteritis. Eur J Epidemiol 4, 366–370 (1988). https://doi.org/10.1007/BF00148926

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