Skip to main content
SpringerLink
Log in

Sinus Histiocytosis with Massive Lymphadenopathy

  • Clinical Report
  • Published:
Indian Journal of Otolaryngology and Head and Neck Surgery Aims and scope Submit manuscript

Abstract

Sinus Histiocytosis with Massive Lymphadenopathy is a very rare condition often presenting as neck swelling of unknown etiology. The disease involves extranodal sites in 20–30 percent of cases and histologically characterized by emperiopolesis, non-cohesive and non-epitheloid histocytes with abundant eosinphilic cytoplasm. An ideal treatment is yet to be established but here we present a short series of chemotherapy with alternating ABVD and COPD cycles giving satisfactory results.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Rosai J, Dorfman RF, Sinus histiocytosis with massive lymphadenopathy: a newly recognized benign clinicopathologic entity. Arch pathol 1969; 63–70

  2. Gupta S, Gupta DC Cytologic appearance of sinus histiocytosis with massive lymphadenopathy. A case report.Acta cytol 1996;40:595–598

    PubMed  CAS  Google Scholar 

  3. Foucar E. Rosai J, Dorfman RF.Sinus histiocytosis with massive lymphadenopathy (Rosai and Dorfman disease): review of the entity.Semin diagn pathol 1990 Feb:7(1)19–73

    PubMed  CAS  Google Scholar 

  4. Bhaskar, Kumaraswamy, Reddy BKM, Supe SS, Rekha V. Sinus histiocytosis with nodal and extranodal involvement: a case report. Journal of Indian medical association Jan 2003:28–31

  5. Mirk, Aftalion B, Kohn LB.Sinus histiocytosis with massive lymphadenopathy and unusual extranodal manifestations.Arch pathol lab med 1985;109:867–870

    Google Scholar 

  6. Foucar E, Roasi J, Dorfman RF.SHML, ear, nose an throat manifestations.Arch otolaryngol 1978 vol104:687–693

    PubMed  CAS  Google Scholar 

  7. Mirra S, Tindall S, Check I, et al.inflammatory meningeal masses of unexplained origin: an ultrastructural and immunological study.J J neuropathol exp neurol 1983;42:453–468

    Article  CAS  Google Scholar 

  8. Thavaray V, Dawar R, Arya LS.Sinus histiocytosis SHML in children.Indian Paediatrics 2002;39:764–769

    Google Scholar 

  9. Palomera L. Domingo JM, Olav T. Romerr S, Guiterrez M. Sinus hitocytosis with massive lymphadenopathy: complete response to low dode infereon alpha.J clin oncol 1997;15:2176

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of ENT, JNMCH, AMU, Aligarh, 202002, Uttar Pradesh

    Samiullah,  Hidayatullah, Nisar H. Dar, Faisal Haque & S. A. Hasan

Authors
  1. Samiullah
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Hidayatullah
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Nisar H. Dar
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Faisal Haque
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. S. A. Hasan
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Samiullah, Hidayatullah, Dar, N.H. et al. Sinus Histiocytosis with Massive Lymphadenopathy. Indian J Otolaryngol Head Neck Surg 58, 277–279 (2006). https://doi.org/10.1007/BF03050840

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03050840

Key words

Search

Navigation