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The Angio-Seal™ hemostatic puncture closure device

Das Angio-Seal™-Verschlußsystem. Konzept und experimentelle Ergebnisse

Concept and experimental results

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Abstract

The Angio-Seal™ hemostatic puncture closure device is the culmination of development efforts dating from 1986. Devel-opment was driven to solve problems of delivering a multi-piece bioabsorbable puncture closure assembly through an introducer, the precise placement of the device in the vessel, the mastery of molding tiny absorbable polymer components, the manufacture of collagen hemostatic sponges having strong tear strength, and the testing of very large samples to establish safety and efficacy. Improvements included in the new 6F device to improve deployment reliability are also discussed.

Zusammenfassung

Das Angio-Seal™-Verschlußsystem (Hemostatic Puncture Closure Device, HPCD) ist das Ergebnis einer langjährigen Entwicklung, die 1986 begonnen hat. Ziel war die Herstellung eines bioresorbierbaren arteriellen Verschlußsystems, welches über ein spezielles Applikationsgerät exakt im Gefäß plaziert werden kann. Hierzu mußte ein dünner absorbierbarer Polymeranker hergestellt werden, dem ein Kollagenschwamm, der unter Druck fixiert wird, gegenübersteht. Um Sicherheit und Wirksamkeit zu testen, wurden zahlreiche Tieruntersuchungen durchgeführt. Kürzlich wurde auch ein 6F-Applikator mit durch weitere Verbesserungen erhöhter Zuverlässigkeit eingeführt.

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Authors and Affiliations

  1. Kensey Nash Corporation, 55 East Uwchlan Avenue, 19341, Exton, PA, USA

    John E. Nash P. E. & Douglas G. Evans P. E.

Authors
  1. John E. Nash P. E.
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  2. Douglas G. Evans P. E.
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Correspondence to Douglas G. Evans P. E..

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Nash, J.E., Evans, D.G. The Angio-Seal™ hemostatic puncture closure device. Herz 24, 597–606 (1999). https://doi.org/10.1007/BF03044483

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  • DOI: https://doi.org/10.1007/BF03044483

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