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Inducing apoptosis of cancer cell and inhibiting mice’s malignant tumour growth by magnetic fields

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Wuhan University Journal of Natural Sciences

Abstract

It was found that the growth of malignant tumour in mice was inhibited and the ability of immune cell’s dissolving cancer cells was enhanced by ultralow frequency (ULF) pulsed gradient magnetic field. The DNA contents of nuclei decreased which indicated that magnetic field can block DNA replication and mitosis of cancer cells. It was observed that magnetic field inhibited the cancer cell’s metabolism, lowered its malignancy, and restrained its rapid and heteromorphic growth. The morphology properties of Programmed Cell Death (PCD) of the cancer cells of the treated group by magnetic field was observed for the first time. The heterochromatin condensed and coagulated together along the nuclear membrane; the endoplasmic reticulums expanded and fused with the cellular membrane; many apoptotic bodies which were packed by the cellular membrane appeared and were devoured by the lymphocytes and plasma.

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Correspondence to Zhang Hu-sheng.

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Foundation item: Supported by the National Natural Science Foundation of China

Biography: ZHANG Hu-sheng(1938-), male, Professor

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Hu-sheng, Z., Xuan-dong, Y., Zong-shan, L. et al. Inducing apoptosis of cancer cell and inhibiting mice’s malignant tumour growth by magnetic fields. Wuhan Univ. J. Nat. Sci. 4, 363–366 (1999). https://doi.org/10.1007/BF02842374

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  • DOI: https://doi.org/10.1007/BF02842374

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