Skip to main content
Log in

Serum and urine ionic fluoride

Normal Range in a Nonexposed Population

  • Original Articles
  • Published:
Biological Trace Element Research Aims and scope Submit manuscript

Abstract

The present study was undertaken to evaluate the fluoride status in the general healthy population of Barcelona. Serum and urine fluoride ionic concentration was determined in a random sample of 250 subjects (age range 15–90 yr) by the Orion fluoride electrode system to determine the normal range of fluoride in this population. The results obtained show that in the general population of Barcelona, fluoride ionic serum concentration ranges between 1 and 47 μg/L (x = 17.5 ± 9.7 μg/L) and fluoride ionic urine concentration ranges between 156 and 1990 μg/24 h (x = 671 ± 373 μg/24 h). The mean serum fluoride concentration of the younger population was shown to be significantly greater (p < 0.05) than that of the older group. No sex-related difference was found.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. J. E. Farley, J. E. Wergedal, and D. J. Baylink, Fluoride directly stimulates proliferation and alkaline phosphatase activity of bone-forming cells,Science 222, 330–332 (1983).

    Article  PubMed  CAS  Google Scholar 

  2. K. Phipps, Fluoride and bone health,J. Public Health Dent. 55(1), 53–56 (1995).

    Article  PubMed  CAS  Google Scholar 

  3. D. G. Pendrys, Risk of fluorosis in a fluoridated population. Implications for the dentist and hygienist,J. Am. Dent. Assoc. 126(2), 1617–1624 (1995).

    PubMed  CAS  Google Scholar 

  4. A. B. Boink, J. Werner, J. Meunleubelt, H. A. Vaessen, and D. J. de Wildt, The mechanism of fluoride-induced hypocalcaemia,Hum. Exp. Toxicol. 13(3), 149–155 (1994).

    PubMed  CAS  Google Scholar 

  5. H. Husdan, R. Vogl, D. Oreopoulos, C. Gryfe, and A. Rapoport, Serum ionic fluoride: normal range and relationship to age and sex,Clin. Chem. 22(11), 1884–1888 (1976).

    PubMed  CAS  Google Scholar 

  6. E. H. Abdennebi, R. Fandi, and D. Lamnaouer, Human fluorosis in Morocco: analytical and clinical investigations,Vet. Hum. Toxicol. 37(5), 465–468 (1995).

    PubMed  CAS  Google Scholar 

  7. R. A. Warpeha and T. M. Marthaler, Urinary fluoride excretion in Jamaica in relation to fluoridated salt,Caries Res. 29(1), 35–41 (1995).

    Article  PubMed  CAS  Google Scholar 

  8. S. Shimonovitz, D. Patz, and P. Ever-Hadani, Umbilical cord fluoride serum levels may not reflect a fetal fluoride status,J. Perinat. Med. 23(4), 279–282 (1995).

    Article  PubMed  CAS  Google Scholar 

  9. F. M. Parkins, N. Tinanoff, and M. Mutinho, Relationships of human plasma fluoride and bone fluoride to age,Calcif. Tissue Res. 16, 335 (1974).

    Article  PubMed  CAS  Google Scholar 

  10. D. F. Davies and N. W. Shock, Ages changes in glomerular filtration rate, effective renal plasma flow and tubular excretory capacity in adult males,J. Clin. Invest. 29, 496 (1950).

    Article  PubMed  CAS  Google Scholar 

  11. E. Fuchs, D. Dorn, and C. A. Fuchs, Fluoride determination in plasma by ion selective electrodes: a simplified method for the clinical laboratory,Clin. Chim. Acta 60, 175 (1975).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Torra, M., Rodamilans, M. & Corbella, J. Serum and urine ionic fluoride. Biol Trace Elem Res 63, 67–71 (1998). https://doi.org/10.1007/BF02785278

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02785278

Index entries

Navigation