Abstract
We herein describe a 27-year-old male presenting with a pulmonary blastoma. The patient was admitted to our hospital with the chief complaints of fever and left back pain. Chest roentgenograms showed a tumor measuring 10 cm in diameter in a lower lobe of the left lung. Computed tomography and magnetic resonance imaging revealed a well demarcated and heterogeneously enhanced tumor. Although a histological diagnosis could not be obtained by a transbronchial biopsy, image analyses led us to suspect it to be malignant. The patient underwent a left lower lobectomy with lymph node dissection. A histopathological examination revealed the tumor to be a biphasic type of pulmonary blastoma. Because of the rapid progress of the tumor and the difficulty in making a preoperative diagnosis in such cases, an immediate surgical resection is therefore recommended in cases with even the slightest suspicion of malignancy.
Article PDF
Similar content being viewed by others
References
Francis D, Jacobsen M (1983) Pulmonary blastoma. Curr Top Pathol 73:265–294
Barrett NR, Barnard WG (1945) Some unusual thoracic tumors. Br J Surg 32:447–457
Spencer H (1961) Pulmonary blastomas. J Pathol Bacteriol 82:161–165
Larsen H, Sorensen JB (1996) Pulmonary blastoma: a review with special emphasis on prognosis and treatment. Cancer Treat Rev 22:145–160
Koss MN, Hochholzer L, O’Leary T (1991) Pulmonary blastomas. Cancer 67:2368–2381
Fung CH, Lo JW, Yonan TN, Milloy FJ, Hakami MM, Changus GW (1977) Pulmonary blastoma: an ultrastructural study with a brief review of literature and a discussion of pathogenesis. Cancer 39:153–163
Martinez JC, Pecero FC, Gutierrez de la Pena C, Gomez RM, Gutierrez del Manzano JA, Flores Corral T, Abril JL (1978) Pulmonary blastoma: report of a case. J Pediatr Surg 13:93–94
Sumner TE, Phelps CRd, Crowe JE, Poolos SP, Shaffner LD (1979) Pulmonary blastoma in a child. Am J Radiol 133:147–148
Valderrama E, Saluja G, Shende A, Lanzkowsky P, Berkman J (1978) Pulmonary blastoma. Report of two cases in children. Am J Surg Pathol 2:415–422
Selle B, Dorffel W, Wit J (1987) Das pulmonale Blastomim Kindesalter—Eine Kasuistik und Uebersicht ueber die Literatur. Z Kinderchir 42:373–377
Kliem V, Bugge M, Leimenstoll K, Maschek H (1992) Pulmonary Blastoma—a rare tumour. Clin Invest 70:927–931
Medbery CA, Bibro MC, Phares JC, Veach SR, Martin JE, Pasquale DN (1984) Pulmonary blastoma. Case report and literature review of chemotherapy experience. Cancer 53;2413–2416
Manivel JC, Priest JR, Watterson J, Steiner M, Woods WG, Wick MR, Dehner LP (1988) Pleuropulmonary blastoma. The so-called pulmonary blastoma of childhood. Cancer 62:1516–1526
Holland-Moritz RM, Heyn RM (1984) Pulmonary blastoma associated with cystic lesions in children. Med Pediatr Oncol 12:85–88
Weinblatt ME, Siegel SE, Isaacs H (1982) Pulmonary blastoma associated with cystic lung disease. Cancer 49:669–671
McCann MP, Fu YS, Kay S (1976) Pulmonary blastoma: a light and electron microscopic study. Cancer 38:789–797
Ozkaynak MF, Ortega JA, Laug W, Gilsanz V, Isaacs H Jr (1990) Role of chemotherapy in pediatric pulmonary blastoma. Med Pediatr Oncol 18:53–56
Lobo-Sanahuja F, Garcia I, Santamaria S, Barrantes JC (1996) Case report: pulmonary blastoma in children—response to chemotherapy. Med Pediatr Oncol 26:196–200
Karcioglu ZA, Someren AO (1974) Pulmonary blastoma. A case report and review of the literature. Am J Clin Pathol 61:287–295
Gibbons JR, McKeown F, Field TW (1981) Pulmonary blastoma with hilar lymph node metastases: survival for 24 years. Cancer 47:152–155
Dienemann D, Hartmann CA, Minck C (1989) Pulmonary blastomas. Immunohistochemical investigations of three cases. Pathol Res Pract 184:306–311
Chejfec G, Cosnow I, Gould NS, Husain AN, Gould VE (1990) Pulmonary blastoma with neuroendocrine differentiation in cell morules resembling neuroepithelial bodies. Histopathology 17:353–358
Heckman CJ, Truong LD, Cagle PT, Font RL (1988) Pulmonary blastoma with rhabdomyosarcomatous differentiation: an electron microscopic and immunohistochemical study. Am J Surg Pathol 12:35–40
Kodama T, Shimosato Y, Watanabe S, Koide T, Naruke T, Shimase J (1984) Six cases of well-differentiated adenocarcinoma simulating fetal lung tubules in pseudoglandular stage. Comparison with pulmonary blastoma. Am J Surg Pathol 8:735–744
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ohara, N., Tominaga, O., Oka, T. et al. Pulmonary blastoma: Report of a case. Surg Today 29, 385–388 (1999). https://doi.org/10.1007/BF02483071
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02483071