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Retention behaviour of selected flavonoid compounds in NP-HPLC

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Summary

HPLC retention data for a number of flavonoid compounds have been evaluated on normal phase silica and cyano colums according to the Soczewinski-Snyder (S.-S.) model. On the silica phase most of the flavones examined exhibited asymetrical peak shapes indicating strong and mixed retention mechanisms; on the cyano phase the intercept of the S.-S. relationship was independent of any hydroxy substitution pattern or of molecular planarity. A similar behaviour, but with different intercept values, was observed with coumarin and quinone compounds.

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Pietrogrande, M.C., Bighi, C., Blo, G. et al. Retention behaviour of selected flavonoid compounds in NP-HPLC. Chromatographia 27, 625–627 (1989). https://doi.org/10.1007/BF02258991

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  • DOI: https://doi.org/10.1007/BF02258991

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