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Prevalence of urinary tract infection during outpatient follow-up after renal transplantation

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Summary

Seven hundred and twenty-seven renal transplant patients are reviewed with respect to the occurrence of urinary tract infection (UTI) after renal transplantation. UTI was defined as the detection of both bacteriuria (105 CFU/ml) and pyuria (10 leukocytes/hpf). UTI developed in 11 of the inpatients (20.8%) and in 30 (4.2%) of the outpatients during a one-year period. Among outpatients, 12 had symptomatic infections, comprising seven with acute pyelonephritis and five with acute cystitis. Asymptomatic UTI was detected in 18 patients. In addition, asymptomatic bacteriuria without pyuria was observed in ten (1.4%) patients. UTI was more common in patients with diabetes, and underlying urinary tract complications were present in some patients. Administration of trimethoprim-sulfamethoxazole for about 4 months is suggested to reduce the frequency of UTI in the early period after renal transplantation.

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References

  1. Walter, S., Pederson, F. B., Vejilsgaard, R. Urinary tract infection and wound infection in kidney transplant patients. Br. J. Urol. 47 (1975) 513–517.

    PubMed  Google Scholar 

  2. Ramsey, D. E., Finch, W. T., Birtch, A. G. Urinary tract infections in kidney transplant recipients. Arch. Surg. 114 (1979) 1022–1025.

    PubMed  Google Scholar 

  3. Hamshere, R. J., Chisholm, G. D., Shackman, R. Late urinary-tract infection after renal transplantation. Lancet ii (1974) 793–794.

    Article  Google Scholar 

  4. Douglas, J. F., Clarke, S., Kennedy, J., McEvoy, J., McGeown, M. G. Urinary-tract infection after renal transplantation. Lancet ii (1974) 1015.

    Article  Google Scholar 

  5. Krieger, J. N., Tapia, L., Stubenbord, W. T., Stenzel, K. H., Rubin, A. L. Urinary infection in kidney transplantation. Urology 9 (1977) 130–136.

    Article  PubMed  Google Scholar 

  6. Byrd, L. H., Tapia, L., Cheigh, J. S., Aronian, J., Stenzel, K. H., Rubin, A. L. Association betweenStreptococcus faecalis urinary infections and graft rejection in kidney transplantation. Lancet ii (1978) 1167–1169.

    Article  Google Scholar 

  7. Griffin, P. J. A., Salaman, J. R. Urinary tract infections after renal transplantation: do they matter? Br. Med. J. 1 (1979) 710–711.

    PubMed  Google Scholar 

  8. Kuzuhara, K., Sugimoto, H., Takahashi, I., Kusaba, R., Yamada, Y., Yamauchi, J., Othubo, O., Akiyama, N., Inou, T. Factors of urological infection after renal transplantation. Jpn. J. Urol. 70 (1979) 200–206.

    Google Scholar 

  9. Belitsky, P., Lannon, S. G., MacDonald, A. S., Cohen, A. D., Marrie, T. J., Houlihan, P., Whalen, A. Urinary tract infections (UTI) after kidney transplantation. Transplant. Proc. 14 (1982) 696–699.

    PubMed  Google Scholar 

  10. Cuvelier, R., Pirson, Y., Alexandre, G. P. J., Strihou, C. Y. Late urinary tract infection after transplantation: prevalence, predisposition and morbidity. Nephron 40 (1985) 76–78.

    PubMed  Google Scholar 

  11. Prát, V., Horčičková, M., Matousovic, K., Hatala, M., Liska, M. Urinary tract infection in renal transplant patients. Infection 13 (1985) 207–210.

    Article  PubMed  Google Scholar 

  12. Tanabe, K., Takahashi, K., Toma, H., Nakazawa, H., Goya, N., Fuchinoue, S., Honda, H., Yagisawa, T., Kawai, T., Teraoka, S., Agishi, T., Yoshida, M., Ota, K. Urinary tract infection in kidney transplant recipients treated with cyclosporin. Jpn. J. Urol. 79 (1988) 246–253.

    Google Scholar 

  13. Maddux, M. S., Veremis, S. A., Bauma, D. W., Pollack, R., Mozes, M. F. Effective prophylaxis of early post-transplant urinary tract infections (UTI) in the cyclosporine (CSA) era. Transplant. Proc. 121 (1989) 2108–2109.

    Google Scholar 

  14. Chan, C. K., Cheng, I. K. P., Wong, K. K., Li, M. K., Chan, M. K. Urinary tract infections in post-renal transplant patients. Int. Urol. Nephrol. 22 (1990) 389–396.

    PubMed  Google Scholar 

  15. Kuriyama, M., Nagai, T., Uno, H., Nishida, Y., Ishihara, T., Kobayashi, K., Takahashi, Y., Saito, A., Kawada, K. Urinary tract infections after kidney transplantation. Acta Urol. Jpn. 37 (1991) 1173–1179.

    Google Scholar 

  16. Renoult, E., Aouragh, F., Mayeux, D., Hestin, D., Lataste, A., Hubert, J., L'Hermite, J., Weber, M., Kessler, M. Factors influencing early urinary tract infections in kidney transplant recipients. Transplant. Proc. 126 (1994) 2056–2058.

    Google Scholar 

  17. Castelao, A. M., Soto, K., Grinyo, J. M., Gilvernet, D., Seron, D., Torras, J., Riera, L., Cruzado, J. M., Alsina, J. Prophylaxis of urinary tract infection in renal transplantation: comparison of three different protocols using ceftriaxone-cloxacillin, aztreonam-cloxacillin, or aztreonam-amoxycillin-clavulanic acid. Transplant. Proc. 27 (1995) 2277–2279.

    PubMed  Google Scholar 

  18. Goya, N., Takahashi, K., Tanabe, K., Osanai, K., Asahina, Y., Oba, S., Ebihagra, K., Nakamura, R., Nakazawa, H., Toma, H., Teraoka, S., Agishi, T., Ota, K., Tostuka, K. Clinical studies of bacteriuria in renal transplantation recipients; correlation with pyuria and symptomatic genitourinary tract infection. Jpn. J. Urol. 82 (1991) 947–954.

    Google Scholar 

  19. Hoy, W. E., Kissel, S. M., Freeman, R. B., Sterling, W. A. Jr. Altered patterns of post-transplant urinary tract infections associated with perioperative antibiotics and curtailed catheterization. Am. J. Kidney Dis. 6 (1985) 212–216.

    PubMed  Google Scholar 

  20. Nathan, A. W., Turner, D. R., Aubrey, C., Cameron, J. S., Williams, D. G., Ogg, C. S., Bewick, M. Corynebacterium hofmannii infection after renal transplantation. Clin. Nephrol. 17 (1982) 315–318.

    PubMed  Google Scholar 

  21. Helmig, R., Uldbjerg, N., Boris, J., Kilian, M. Clonal analysis ofStreptococcus agalactiae isolated from infants with neonatal sepsis or meningitis and their mothers and from healthy pregnant women. J. Infect. Dis. 168 (1993) 904–909.

    PubMed  Google Scholar 

  22. Zozikov, B., Girgitzova, B., Minkov, N. Problems in the treatment of urinary tract infections caused byStreptococcus agalactiae. Int. Urol. Nephrol. 25 (1993) 409–415.

    PubMed  Google Scholar 

  23. Thompson, J. F., Chalmers, D. H. K., Hunnisett, A. G. W., Wood, R. F. M., Morris, P. J. Nephrotoxicity and trimethoprim and co-trimoxazole in renal allograft recipients treated with cyclosporin. Transplantation 36 (1983) 204–206.

    PubMed  Google Scholar 

  24. Rubin, R. H. Infectious disease complications of renal transplantation. Kidney Int. 44 (1993) 221–235.

    PubMed  Google Scholar 

  25. Tolkoff-Rubin, N. E., Cosimi, A. B., Russell, P. S., Rubin, R. H. A controlled study of trimethoprim-sulfamethoxazole prophylaxis of urinary tract infection in renal transplant recipients. Rev. Infect. Dis. 4 (1982) 614–618.

    PubMed  Google Scholar 

  26. Vogt, P., Schorn, T., Frei, U. Ofloxacin in the treatment of urinary tract infection in renal transplant recipients. Infection 16 (1988) 175–178.

    Article  PubMed  Google Scholar 

  27. Peters, C., Peterson, P., Marabella, P., Simmons, R. L., Najarian, J. S. Continuous sulfa prophylaxis for urinary tract infection in renal transplant recipients. Am. J. Surg. 146 (1983) 589–593.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Dept. of Urology, Tokyo Women's Medical College, 8-1 Kawada-cho, Shinjuku-ku, 162, Tokyo, Japan

    N. Goya M. D., K. Tanabe M. D., Y. Iguchi M. D., T. Oshima M. D., T. Yagisawa M. D. & H. Toma M. D.

  2. Third Dept. of Surgery, Kidney Center, Tokyo Women's Medical College, 8-1 Kawada-cho, Shinjuku-ku, 162, Tokyo, Japan

    T. Agishi M. D. & K. Ota M. D.

  3. Dept. of Urology, Niigata University, Ichiban-cho, Asahimatidohri, Niigata-shi, 951, Niigata, Japan

    K. Takahashi M. D.

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  1. N. Goya M. D.
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  2. K. Tanabe M. D.
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  3. Y. Iguchi M. D.
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  4. T. Oshima M. D.
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  5. T. Yagisawa M. D.
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  6. H. Toma M. D.
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  7. T. Agishi M. D.
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  8. K. Ota M. D.
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  9. K. Takahashi M. D.
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Goya, N., Tanabe, K., Iguchi, Y. et al. Prevalence of urinary tract infection during outpatient follow-up after renal transplantation. Infection 25, 101–105 (1997). https://doi.org/10.1007/BF02113586

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  • DOI: https://doi.org/10.1007/BF02113586

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