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The EOG and choroidal malignant melanomas

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Abstract

Fifty-four patients with a unilateral pigmented choroidal lesion were studied with electrooculography (EOG). Eighteen of 21 patients with histologically proven (13) or presumed (8) malignant tumors of the choroid had light peak-dark trough ratios (L/D) ⩽ 150. Seventeen of 21 patients in the malignant group had an interocular L/D difference (L/Dd) ⩾ 23%, whereas only one of 33 patients with nevi or a condition simulating a nevus had a percent difference of such magnitude. Combining the L/D and L/Dd criteria resulted in a 98% accurate double-blind prediction of the final clinical/pathological results. The EOG is an objective, noninvasive test useful in the diagnosis of choroidal malignant melanomas.

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Author notes

  1. James A. Staman,  Constance R. Fitzgerald, William W. Dawson, Michael C. Barris & C. Ian Hood

    Present address: Departments of Ophthalmology, Physiology and Pathology College of Medicine University of Florida, 32610, Gainesville, Florida, USA

Authors and Affiliations

  1. Gainesville, Florida, USA

    James A. Staman,  Constance R. Fitzgerald, William W. Dawson, Michael C. Barris & C. Ian Hood

  2. Department of Ophthalmology, USA

    Constance R. Fitzgerald

Authors
  1. James A. Staman
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  2. Constance R. Fitzgerald
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  3. William W. Dawson
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  4. Michael C. Barris
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  5. C. Ian Hood
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Staman, J.A., Fitzgerald, C.R., Dawson, W.W. et al. The EOG and choroidal malignant melanomas. Doc Ophthalmol 49, 201–209 (1980). https://doi.org/10.1007/BF01886618

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