Abstract
The aetiology of the Shy—Drager syndrome (multiple system atrophy) is unknown. We reported previously a preliminary association between environmental—occupational risk factors and Shy—Drager syndrome. To further investigate this relationship, we evaluated olfactory function in eight patients in different stages of disease. When the eight patients' olfactory function was compared with 203 age- and sex-matched controls using a selfadministered olfactory test, seven scored below the 39th percentile of this population. Five of the eight patients had total anosmia or microsmia. Additional studies will be required to elucidate the significance of this abnormal clinical observation.
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Nee, L.E., Scott, J. & Polinsky, R.J. Olfactory dysfunction in the Shy—Drager syndrome. Clinical Autonomic Research 3, 281–282 (1993). https://doi.org/10.1007/BF01829019
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DOI: https://doi.org/10.1007/BF01829019