Abstract
Evaporation cycles applied to dilute solutions of amino acids, Cu(II) and NaCl lead to peptides within 1–3 days. This simulation of possible coastal or laguna processes in a primitive earth environment gives further indications towards the relevance of the salt-induced peptide formation reaction in chemical evolution. The experiments were successfully applied to glycine, alanine, aspartic and glutamic acid. Besides isolated amino acids, also their mixtures with glycine as reaction partner were studied, leading to peptides for all of the aforementioned substances, as well as for valine and proline, which do not dimerize alone. Sequence preferences and some conservation of optical purity were observed.
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Saetia, S., Liedl, K.R., Eder, A.H. et al. Evaporation cycle experiments — A simulation of salt-induced peptide synthesis under possible prebiotic conditions. Origins Life Evol Biosphere 23, 167–176 (1993). https://doi.org/10.1007/BF01581836
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DOI: https://doi.org/10.1007/BF01581836