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Identification of a protein encoded in the EB-viral open reading frame BMRF 2

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Summary

Using monospecific rabbit sera against a peptide derived from a potential antigenic region of the Epstein-Barr viral amino acid sequence encoded in the open reading frame BMRF 2 we could identify a protein-complex of 53/55 kDa in chemically induced B 95-8, P3HR1 and Raji cell lines. This protein could be shown to be membrane-associated, as predicted by previous computer analysis of the secondary structure and hydrophilicity pattern, and may be a member of EBV-induced membrane proteins in lytically infected cells.

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Author notes

  1. Brigitte Höflacher

    Present address: Mikrogen GmbH, Munich, Germany

Authors and Affiliations

  1. Max von Pettenkofer-Institut, Munich

    Susanne Modrow & H. Wolf

  2. Gesellschaft für Strahlen- und Umweltforschung, Neuherberg, Germany

    Brigitte Höflacher

  3. Institut für Medizinische Mikrobiologie und Hygiene, Universität Regensburg, Franz-Josef-Strauß-Allee 11, D-W-8400, Regensburg, Germany

    Susanne Modrow

Authors
  1. Susanne Modrow
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  2. Brigitte Höflacher
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  3. H. Wolf
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Modrow, S., Höflacher, B. & Wolf, H. Identification of a protein encoded in the EB-viral open reading frame BMRF 2. Archives of Virology 127, 379–386 (1992). https://doi.org/10.1007/BF01309601

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  • DOI: https://doi.org/10.1007/BF01309601

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