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Agarose-chymotrypsin as a catalyst for peptide and amino acid ester synthesis in organic media

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Summary

Chymotrypsin immobilised within agarose gels by multi-point covalent attachment is a useful catalyst for peptide or amino acid ester synthesis in mainly organic media. Moist gel beads (optionally containing one reactant) may be suspended in organic phases based on ethyl acetate, 1,1,1-trichloroethane or pentan-3-one.

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Authors and Affiliations

  1. Department of Bioscience & Biotechnology, University of Strathclyde, G1 1XW, Glasgow, UK

    Rosa M. Blanco & Peter J. Halling

  2. Instituto de Catalisis y Petroleoquimica, C.S.I.C., Serrano 119, 28006, Madrid, Spain

    Rosa M. Blanco & José M. Guisán

Authors
  1. Rosa M. Blanco
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  2. José M. Guisán
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  3. Peter J. Halling
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Blanco, R.M., Guisán, J.M. & Halling, P.J. Agarose-chymotrypsin as a catalyst for peptide and amino acid ester synthesis in organic media. Biotechnol Lett 11, 811–816 (1989). https://doi.org/10.1007/BF01026103

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  • DOI: https://doi.org/10.1007/BF01026103

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